Ovarian cancer rates declining in breast cancer survivors

Ovarian cancer rates declining in breast cancer survivors
Primary ovarian cancer incidence is declining in the United States, both among the general population and among breast cancer survivors, according to research published online Jan. 2 in the Journal of Clinical Oncology.

(HealthDay)—Primary ovarian cancer incidence is declining in the United States, both among the general population and among breast cancer survivors, according to research published online Jan. 2 in the Journal of Clinical Oncology.

Sara J. Schonfeld, Ph.D., M.P.H., from the National Institutes of Health in Bethesda, Md., and colleagues analyzed data from the Surveillance, Epidemiology, and End Results program (1973 to 2008) to examine the incidence of second primary ovarian cancers among .

The researchers found that, over the entire study period, the standardized incidence ratios (SIRs) for second primary were elevated (SIR, 1.24), while the absolute rates decreased by about 1 percent per year. Similar secular trends were observed for second ovarian cancers following estrogen receptor (ER)-positive and ER-negative breast cancers, although there were significant variations in the age-specific patterns based on ER expression. Women aged younger than 50 years with ER-negative breast cancer had the largest SIR (SIR, 4.35).

"Persistently elevated SIRs along with decreasing absolute rates over the entire study period suggest that ovarian cancers in both the general population and survivors of are declining in parallel, possibly because of common risk factor exposures," the authors write. "Analytic studies are needed to further assess the parallel overall trends and the age-specific interaction by ER expression."

More information: Abstract
Full Text (subscription or payment may be required)

add to favorites email to friend print save as pdf

Related Stories

Coffee reduces breast cancer risk: new study

May 11, 2011

Recently published research shows that coffee drinkers enjoy not only the taste of their coffee but also a reduced risk of cancer with their cuppa. More detailed research published today in BioMed Central's open access journal ...

Recommended for you

User comments