T1DM insulin intensification patterns, outcomes studied

T1DM insulin intensification patterns, outcomes studied
About half of youths with type 1 diabetes shift to a more intensive insulin regimen over time, which is associated with better glycemic control, according to research published in the January issue of Diabetes Care.

(HealthDay)—About half of youths with type 1 diabetes shift to a more intensive insulin regimen over time, which is associated with better glycemic control, according to research published in the January issue of Diabetes Care.

Catherine Pihoker, M.D., of the University of Washington in Seattle, and colleagues examined the patterns and associations of insulin regimens and change in regimens with clinical outcome in a study involving 1,606 youth with recently diagnosed .

The researchers found that, during 36 months of follow-up, 51.7 percent of participants changed to a more intensive regimen, 44.7 percent had no change, and 3.6 percent shifted to a less intensive regimen. Younger participants, non-Hispanic whites, and those from families with higher income and and with were more likely to change to a more intensive regimen or experience no change. Compared with those who changed to a less intensive regimen, those with no change or who changed to a more intensive regimen had significantly lower baseline and smaller increases in A1C over time. The probability of achieving target A1C levels was higher for participants with younger age, continuous subcutaneous insulin pump therapy, and those who changed to a more intensive regimen.

"For the majority of youth in this study, insulin regimen intensified over time, and more intensive regimens were associated with lower A1C," the authors write. "Taking together the better outcomes but sociodemographic disparities in intensification of insulin regimens, there is a dire need to develop strategies to improve care for all children with diabetes."

More information: Abstract
Full Text (subscription or payment may be required)

add to favorites email to friend print save as pdf

Related Stories

Treating diabetes

Jan 29, 2010

(PhysOrg.com) -- Uncontrolled high blood glucose levels in patients with diabetes (hyperglycaemia) is known to increase mortality, but new research led by the University shows that intensive treatment to control ...

Recommended for you

Diabetes and Thanksgiving can live in harmony

Nov 25, 2014

As you may know, November is National Diabetes Month. If you, a loved one, or a Thanksgiving guest have diabetes or prediabetes, this column is dedicated to you, as you may be wondering how to enjoy one of the most food-laden ...

Does a yogurt a day keep diabetes away?

Nov 24, 2014

A high intake of yogurt has been found to be associated with a lower risk of developing type 2 diabetes, according to research published in open access journal BMC Medicine. This highlights the importance of hav ...

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.