Tomosynthesis ups accuracy of digital mammography

January 4, 2013
Tomosynthesis ups accuracy of digital mammography
Using a combination of tomosynthesis, which produces a three-dimensional reconstruction of the breast, with digital mammography increases radiologists' diagnostic accuracy and significantly lowers the number of recalls for non-cancer cases, according to research published in the January issue of Radiology.

(HealthDay)—Using a combination of tomosynthesis, which produces a three-dimensional reconstruction of the breast, with digital mammography increases radiologists' diagnostic accuracy and significantly lowers the number of recalls for non-cancer cases, according to research published in the January issue of Radiology.

Elizabeth A. Rafferty, M.D., of Massachusetts General Hospital in Boston, and colleagues conducted a multicenter, multireader trial involving 1,192 women who had mediolateral oblique and craniocaudal digital mammographic and tomosynthesis images taken of both breasts. Radiologists' diagnostic accuracy and recall rates were compared for tomosynthesis and mammography versus mammography alone.

The researchers found that adding tomosynthesis to significantly increased diagnostic accuracy for all 27 radiologists who read images. Additionally, the recall rates were significantly reduced with the addition of tomosynthesis to digital mammography. Finally, the sensitivity of the combined approach was most improved for invasive cancers, which improved by 15 to 22 percent, compared with in situ cancers, which was associated with a 3 percent increase in sensitivity.

"In conclusion, the addition of tomosynthesis to digital mammography offers the dual benefit of improved and significant reduction in false-positive recall rate thereby avoiding unnecessary additional testing and decreasing attendant anxiety, inconvenience, and cost for women," the authors write.

Several authors disclosed financial ties to the medical device industry. One author provides expert testimony in malpractice cases.

Explore further: Novel breast screening technology increases diagnostic accuracy

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

New technology offers the next generation of mammography

October 1, 2011

Breast cancer is the second most common type of cancer among women in the United States, with approximately 200,000 new diagnoses each year. Early detection is key in the treatment of breast cancer and the biggest advancement ...

Recommended for you

Study: Enhancing cancer response to radiation

December 2, 2016

OHSU researcher Sudarshan Anand, Ph.D., has a contemporary analogy to describe microRNA: "I sometimes compare MicroRNA to tweets—they're short, transient and constantly changing."

Rare childhood disease linked to major cancer gene

December 1, 2016

A team of researchers led by a University of Rhode Island scientist has discovered an important molecular link between a rare childhood genetic disease, Fanconi anemia, and a major cancer gene called PTEN. The discovery improves ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.