Tomosynthesis ups accuracy of digital mammography

Tomosynthesis ups accuracy of digital mammography
Using a combination of tomosynthesis, which produces a three-dimensional reconstruction of the breast, with digital mammography increases radiologists' diagnostic accuracy and significantly lowers the number of recalls for non-cancer cases, according to research published in the January issue of Radiology.

(HealthDay)—Using a combination of tomosynthesis, which produces a three-dimensional reconstruction of the breast, with digital mammography increases radiologists' diagnostic accuracy and significantly lowers the number of recalls for non-cancer cases, according to research published in the January issue of Radiology.

Elizabeth A. Rafferty, M.D., of Massachusetts General Hospital in Boston, and colleagues conducted a multicenter, multireader trial involving 1,192 women who had mediolateral oblique and craniocaudal digital mammographic and tomosynthesis images taken of both breasts. Radiologists' diagnostic accuracy and recall rates were compared for tomosynthesis and mammography versus mammography alone.

The researchers found that adding tomosynthesis to significantly increased diagnostic accuracy for all 27 radiologists who read images. Additionally, the recall rates were significantly reduced with the addition of tomosynthesis to digital mammography. Finally, the sensitivity of the combined approach was most improved for invasive cancers, which improved by 15 to 22 percent, compared with in situ cancers, which was associated with a 3 percent increase in sensitivity.

"In conclusion, the addition of tomosynthesis to digital mammography offers the dual benefit of improved and significant reduction in false-positive recall rate thereby avoiding unnecessary additional testing and decreasing attendant anxiety, inconvenience, and cost for women," the authors write.

Several authors disclosed financial ties to the medical device industry. One author provides expert testimony in malpractice cases.

More information: Abstract
Full Text (subscription or payment may be required)

add to favorites email to friend print save as pdf

Related Stories

Recommended for you

Discovery could lead to new cancer treatment

Aug 29, 2014

A team of scientists from the University of Colorado School of Medicine has reported the breakthrough discovery of a process to expand production of stem cells used to treat cancer patients. These findings could have implications ...

Is the HPV vaccine necessary?

Aug 29, 2014

As the school year starts in full swing many parents wonder if their child should receive the HPV vaccine, which is recommended for girls ages 11-26 and boys 11-21. There are a lot of questions and controversy around this ...

User comments