Adiposity, hyperglycemia tied to cognitive performance

Adiposity, hyperglycemia tied to cognitive performance
Among healthy middle-aged adults, adiposity and hyperglycemia correlate with poor cognitive performance, according to a study published online Dec. 28 in Diabetes Care.

(HealthDay)—Among healthy middle-aged adults, adiposity and hyperglycemia correlate with poor cognitive performance, according to a study published online Dec. 28 in Diabetes Care.

Caroline M. Sanz, M.D., from the University of Toulouse in France, and colleagues examined the correlation between markers of , markers of adiposity, (HbA1c), and cognitive performance in a sample of 1,172 adults aged 35 to 64 years without diabetes.

The researchers found that, in tests evaluating processing speed, elevated markers of adiposity correlated with poor cognitive performance. In each test, the probability of being in the lowest quartile was significantly increased for participants in the upper versus the lowest quartile of (adjusted odds ratio [OR], 2.18 for digit symbol substitution test [DSST]; OR, 2.09 for Stroop test). Poor cognitive performance in the DSST was also significantly more likely for those with high HbA1c (adjusted OR, 1.75). In men, but not women, was linked to poor cognitive performance.

"In a population of middle-aged adults without diabetes, we found that adiposity and a high level of HbA1c were both associated with poor cognitive performance in tests assessing processing speed," the authors write.

More information: Abstract
Full Text (subscription or payment may be required)

add to favorites email to friend print save as pdf

Related Stories

Recommended for you

Team shows why wound healing is impaired in diabetics

Jan 26, 2015

One of the most troubling complications of diabetes is its effect on wound healing. Roughly 15 percent of diabetics will suffer from a non-healing wound in their lifetime. In some cases, these open ulcers on the skin lead ...

Progress in diabetes drug delivery

Jan 22, 2015

A drug therapy for diabetes treatment is being developed by an international research team led by WA scientists, which combines an existing anti-diabetic drug with bile acids to improve the drug's delivery ...

Roux-en-Y surgery can reverse insulin treatment in T2DM

Jan 21, 2015

(HealthDay)—Roux-en-Y gastric bypass surgery (RYGB) strongly predicts insulin cessation after surgery in insulin-treated type 2 diabetes (I-T2D) patients, independent of weight loss, according to a study ...

User comments

Adjust slider to filter visible comments by rank

Display comments: newest first

marble89
not rated yet Feb 02, 2013
Doesn't it make sense that having a poor BMI is associated with a poor sell image which in turn is a marker of depression. If you are depressed your cognitive perfornance suffers

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.