Adiposity, hyperglycemia tied to cognitive performance

February 1, 2013
Adiposity, hyperglycemia tied to cognitive performance
Among healthy middle-aged adults, adiposity and hyperglycemia correlate with poor cognitive performance, according to a study published online Dec. 28 in Diabetes Care.

(HealthDay)—Among healthy middle-aged adults, adiposity and hyperglycemia correlate with poor cognitive performance, according to a study published online Dec. 28 in Diabetes Care.

Caroline M. Sanz, M.D., from the University of Toulouse in France, and colleagues examined the correlation between markers of , markers of adiposity, (HbA1c), and cognitive performance in a sample of 1,172 adults aged 35 to 64 years without diabetes.

The researchers found that, in tests evaluating processing speed, elevated markers of adiposity correlated with poor cognitive performance. In each test, the probability of being in the lowest quartile was significantly increased for participants in the upper versus the lowest quartile of (adjusted odds ratio [OR], 2.18 for digit symbol substitution test [DSST]; OR, 2.09 for Stroop test). Poor cognitive performance in the DSST was also significantly more likely for those with high HbA1c (adjusted OR, 1.75). In men, but not women, was linked to poor cognitive performance.

"In a population of middle-aged adults without diabetes, we found that adiposity and a high level of HbA1c were both associated with poor cognitive performance in tests assessing processing speed," the authors write.

Explore further: Obesity, weight gain in middle age associated with increased risk of diabetes among older adults

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Sleep apnea severity linked to glycated hemoglobin levels

June 18, 2012

(HealthDay) -- For adults without diabetes, obstructive sleep apnea (OSA) severity is independently associated with impaired glucose metabolism, as measured by glycated hemoglobin (HbA1c) levels, according to a study published ...

White matter structural changes ID'd in children with T1DM

September 17, 2012

(HealthDay)—Children with type 1 diabetes have significant structural differences in the white matter of their brain compared to healthy children, which correlates with hemoglobin A1c (HbA1c) values, according to a study ...

Meds adherence self-report valid in type 2 diabetes

December 20, 2012

(HealthDay)—Self-reported measures of medication adherence in adults with type 2 diabetes are valid, although some self-reports are moderated by depression, according to a study published online Nov. 30 in Diabetes Care.

Recommended for you

Diets avoiding dry-cooked foods can protect against diabetes

August 24, 2016

Simple changes in how we cook could go a long way towards preventing diabetes, say researchers at the Icahn School of Medicine at Mount Sinai. A new randomized controlled trial, published online July 29 in the journal Diabetologia, ...

New study reveals a novel protein linked to type 2 diabetes

August 16, 2016

Findings from Boston University School of Medicine (BUSM), which appear in eLife, provide a possible explanation as to why most people who are obese develop insulin resistance and type 2 diabetes. A minority of obese individuals, ...

Gene variant explains differences in diabetes drug response

August 9, 2016

The first results from a large international study of patients taking metformin, the world's most commonly used type 2 diabetes drug, reveal genetic differences among patients that may explain why some respond much better ...

1 comment

Adjust slider to filter visible comments by rank

Display comments: newest first

not rated yet Feb 02, 2013
Doesn't it make sense that having a poor BMI is associated with a poor sell image which in turn is a marker of depression. If you are depressed your cognitive perfornance suffers

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.