Depressed patients less likely to complete cardiac rehab

February 15, 2013
Depressed patients less likely to complete cardiac rehab
Depressed patients are less likely to complete exercise-based, cardiac rehabilitation programs, regardless of whether they are taking antidepressants, according to a study published in the Feb. 1 issue of The American Journal of Cardiology.

(HealthDay)—Depressed patients are less likely to complete exercise-based, cardiac rehabilitation programs, regardless of whether they are taking antidepressants, according to a study published in the Feb. 1 issue of The American Journal of Cardiology.

Neil F. Gordon, M.D., Ph.D., from INTERVENT International in Savannah, Ga., and colleagues analyzed data from 26,957 patients who had completed a baseline assessment before participating in a 12-week exercise-based . Based on baseline self-reported history of depression and the current use of antidepressants, patients were stratified into three cohorts: non-depressed, depressed unmedicated, and depressed medicated).

The researchers found that 19.2 percent of patients self-reported a history of depression at baseline, with 41.5 percent of these patients taking antidepressants. Patients in the non-depressed cohort were significantly more likely to complete the exit assessment than patients in the depressed unmedicated or the depressed medicated cohorts (49.4 percent completion versus 44.5 and 43.5 percent, respectively). In all three cohorts, significant improvements were noted in multiple risk factors for those who completed the exit assessment. The magnitude of improvement was similar in measures of blood pressure, serum lipids and lipoproteins, fasting glucose, weight, and for patients taking antidepressants and those who were not.

"Given the high prevalence of depression and the compelling evidence that it substantially increases the risk of events, the present data have important implications for physicians and payers of ," the authors write. "Specifically, our findings serve to further highlight the need to optimize secondary prevention program referral, participation, and compliance for patients with a history of depression, including those treated with antidepressants."

Several authors disclosed financial ties to INTERVENT, a lifestyle management and chronic disease risk reduction company.

Explore further: Ibuprofen, aspirin, other anti-inflammatory drugs reduce effectiveness of SSRI antidepressants

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Statins linked with lower depression risk in heart patients

February 24, 2012

Patients with heart disease who took cholesterol-lowering statins were significantly less likely to develop depression than those who did not, in a study by Mary Whooley, MD, a physician at the San Francisco VA Medical Center ...

Hepatitis C drug can cause depression

May 1, 2012

There's a high rate of depression among patients with hepatitis C, but a standard treatment for the disease includes a drug, interferon, that can cause depression.

Recommended for you

Heart attack treatment hypothesis 'busted'

July 6, 2015

Researchers have long had reason to hope that blocking the flow of calcium into the mitochondria of heart and brain cells could be one way to prevent damage caused by heart attacks and strokes. But in a study of mice engineered ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.