Post-pregnancy deterioration in glycemic control in T1DM

February 14, 2013
Post-pregnancy deterioration in glycemic control in T1DM
Women with type 1 diabetes experience post-pregnancy deterioration in glycemic control and sustained weight gain, according to research published online Dec. 18 in Diabetes Care.

(HealthDay)—Women with type 1 diabetes experience post-pregnancy deterioration in glycemic control and sustained weight gain, according to research published online Dec. 18 in Diabetes Care.

Katarzyna Cyganek, M.D., Ph.D., of the University Hospital in Krakow, Poland, and colleagues examined post-pregnancy glycemic control and weight changes in 254 women (mean age, 28.3 years) with (duration, 12.0 ± 7.7 years) who had singleton pregnancies. The women were followed post-delivery for a median of 20 months.

The researchers found that the mean A1C decreased from 6.9 percent preconception to 5.7 percent during the third trimester. The mean weight gain during pregnancy was 14.4 kg. Within six months of delivery, A1C increased significantly, by 0.8 percent versus the last trimester, and it further deteriorated by 0.8 percent up to the end of follow-up. Compared with preconception baseline, body weight was 4.4 kg higher and was 2.5 kg/m² higher within six months after delivery, and were 2.5 kg and 0.9 kg/m² higher, respectively, at the end of follow-up. Women with planned pregnancies (117 women) experienced worse A1C at more than 12 months after delivery compared with before conception, while for women with unplanned pregnancies the level was similar to that of pre-gestation.

"In conclusion, type 1 diabetic women showed post-pregnancy deterioration in glycemic control. They were also unable to return to their pre-pregnancy weight," the authors write. "Type 1 diabetic women seem to require special medical attention after delivery to maintain their within therapeutic targets."

Explore further: Mothers' weight before and during pregnancy affects baby's weight

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Pre-op factors predict post-gastric op glycemic response

October 8, 2012

(HealthDay)—The glycemic response to gastric bypass surgery can be predicted in Chinese patients with type 2 diabetes by three preoperative factors, according to a study published online Oct. 1 in Diabetes Care.

Recommended for you

Older people getting smarter, but not fitter

August 31, 2015

Older populations are scoring better on cognitive tests than people of the same age did in the past —a trend that could be linked to higher education rates and increased use of technology in our daily lives, say IIASA population ...

Higher intelligence score means better physical performance

August 14, 2015

New research reveals a distinct association between male intelligence in early adulthood and their subsequent midlife physical performance. The higher intelligence score, the better physical performance, the study reveals. ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.