Cardio risks need evaluation before prescribing statins

Cardio risks need evaluation before prescribing statins
Physicians may not adequately consider a patient's cardiovascular risk when prescribing statins as preventive therapy, according to a research letter published online March 11 in JAMA Internal Medicine.

(HealthDay)—Physicians may not adequately consider a patient's cardiovascular risk when prescribing statins as preventive therapy, according to a research letter published online March 11 in JAMA Internal Medicine.

Michael E. Johansen, M.D., from University of Michigan in Ann Arbor, and colleagues anonymously surveyed 750 physicians selected randomly from a nationally representative sample of U.S. physicians from the American Medical Association Physician Masterfile. There were an equal number of family medicine, cardiology, and general internal medicine physicians in the sample. Six vignette-style questions involving patients without and different baseline risks were included in the survey, with vignette numbers three to six including patients who had attempted .

The researchers analyzed 202 usable, returned samples. They found in vignettes one and two that when a woman with diabetes had higher levels of low-density lipoprotein cholesterol (LDL-C) (120 versus 88 mg/dL), statin therapy was recommended significantly more often (94 versus 40.2 percent). In vignettes three and four, significantly more treated a low-risk (LDL-C level of 180 mg/dL) 40-year-old man with well-controlled hypertension (88.9 percent) compared with a low-risk 50-year-old women (73.5 percent). In vignettes five and six, with hypertensive, tobacco-using patients, similar treatment rates were recommended to a 75-year-old man (LDL-C level of 140 mg/dL) compared with a 50-year-old woman (LDL-C level of 145 mg/dL). There were no differences in responses by clinical specialty.

"Overall, our study suggests that physicians may not adequately consider a patient's when prescribing statins in primary prevention," the authors write.

More information: Full Text (subscription or payment may be required)

add to favorites email to friend print save as pdf

Related Stories

More patients across the world lowering 'bad' cholesterol

Jun 22, 2009

The percentage of patients lowering their elevated "bad" cholesterol to within target levels nearly doubled in the last decade, according to a multi-national survey reported in Circulation: Journal of the American Heart As ...

Recommended for you

Gene variant raises risk for aortic tear and rupture

Apr 17, 2014

Researchers from Yale School of Medicine and Celera Diagnostics have confirmed the significance of a genetic variant that substantially increases the risk of a frequently fatal thoracic aortic dissection or full rupture. ...

Considerable variation in CT use in ischemic stroke

Apr 17, 2014

(HealthDay)—For patients with ischemic stroke there is considerable variation in the rates of high-intensity computed tomography (CT) use, according to a study published online April 8 in Circulation: Ca ...

Beating the clock for ischemic stroke sufferers

Apr 17, 2014

A ground-breaking computer technology raises hope for people struck by ischemic stroke, which is a very common kind of stroke accounting for over 80 per cent of overall stroke cases. Developed by research experts at The Hong ...

User comments