Circulatory system mortality declining in Hodgkin's

Circulatory system mortality declining in hodgkin's
Among patients treated for Hodgkin's lymphoma, long-term excess mortality due to diseases of the circulatory system is expected to continue to decline, according to research published online Feb. 25 in the Journal of Clinical Oncology.

(HealthDay)—Among patients treated for Hodgkin's lymphoma (HL), long-term excess mortality due to diseases of the circulatory system (DCS) is expected to continue to decline, according to research published online Feb. 25 in the Journal of Clinical Oncology.

In an effort to estimate the treatment-related mortality caused by DCS, Sandra Eloranta, of the Karolinska Institute in Stockholm, and colleagues used population-based data for 5,462 patients diagnosed with and treated for HL between 1973 and 2006.

The researchers note that, since the mid-1980s, DCS mortality in HL patients has steadily declined. Patients who were older when diagnosed and men were at higher risk of death due to DCS. After accounting for other causes of death, the number of deaths attributed to HL treatment-related DCS was actually only a small proportion.

"This study shows how the long-term excess DCS mortality experienced by patients with HL in Sweden, diagnosed and treated in the 1990s and early 2000s, is expected to further decrease compared with that of patients diagnosed in earlier years. A similar, but stronger, trend is also observed for the remaining excess HL mortality," the authors write. "The improvements in survival are not likely to be explained by changes in disease characteristics (i.e., a more favorable distribution of in recent years)."

More information: Abstract
Full Text (subscription or payment may be required)

add to favorites email to friend print save as pdf

Related Stories

HIV status doesn't influence Hodgkin's lymphoma outcome

Oct 11, 2012

(HealthDay)—Despite more extensive disease and more adverse prognostic factors, HIV-positive patients with Hodgkin's lymphoma (HL) do not have worse outcomes when treated with doxorubicin, bleomycin, vinblastine, ...

Ulcerative colitis, not crohn's, deaths down from 1982

Jan 21, 2013

(HealthDay)—Over the past 30 years in Denmark, mortality from ulcerative colitis (UC) has decreased, but mortality from Crohn's disease (CD) has remained persistently higher than the general population, ...

Recommended for you

Putting the brakes on cancer

15 hours ago

A study led by the University of Dundee, in collaboration with researchers at our University, has uncovered an important role played by a tumour suppressor gene, helping scientists to better understand how ...

Peanut component linked to cancer spread

16 hours ago

Scientists at the University of Liverpool have found that a component of peanuts could encourage the spread and survival of cancer cells in the body.

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.