Family intervention improves mood symptoms in children and adolescents at risk for bipolar disorder
A study published in the February 2013 issue of the Journal of the American Academy of Child and Adolescent Psychiatry found that children and adolescents with major depression or subthreshold forms of bipolar disorder - and who had at least one first-degree relative with bipolar disorder - responded better to a 12-session family-focused treatment than to a briefer educational treatment.
A study led by David J. Miklowitz, Ph.D., of the UCLA School of Medicine, and Kiki D. Chang, M.D., of Stanford University School of Medicine, identified 40 youth (average age 12 years) who were at risk for developing bipolar disorder. The participants had diagnoses of major depressive disorder, cyclothymic disorder, or bipolar disorder, not otherwise specified (NOS) (brief and recurrent episodes of mania or hypomania that did not meet full diagnostic criteria for bipolar disorder), and had at least one first-degree relative (usually a parent) with bipolar I or II disorder. The investigators randomly assigned the 40 participants to family-focused treatment, high-risk version (FFT-HR), consisting of 12 family sessions over 4 months of psychoeducation (learning strategies to manage mood swings), communication skills training, or problem-solving skills training; or 1-2 family informational sessions (educational control, or EC). Of the 40 participants, 60% were taking psychiatric medications upon entry, and continued taking recommended medications throughout the study. Half of the participants were recruited and treated at the University of Colorado, Boulder, and half at Stanford University.
Participants in the FFT-HR condition recovered from their initial depressive symptoms in an average of 9 weeks, compared to 21 weeks in the EC condition. Participants who received FFT-HR also had more weeks in full remission from mood symptoms over the study year. Improvements in mania symptoms on the Young Mania Rating Scale were greater in the FFT-HR group as well.
The study participants who lived in families that were rated high in expressed emotion, a measure of critical comments or emotional overprotectiveness in parents, took almost twice as long to recover from their mood symptoms as those in families rated low in expressed emotion. A secondary analysis indicated that youth from high expressed emotion families who were treated with FFT-HR spent more weeks in remission over the year than those treated with EC.
Dr. Miklowitz cautioned that the length of follow-up (1 year) was too short to determine whether these children would develop full bipolar disorder. "Nonetheless," he said, "catching bipolar disorder at its earliest stages, stabilizing symptoms that have already developed, and helping the family to cope effectively with the child's mood swings may have downstream effects that improve the long-term outcomes of high-risk children."
More information: The article "Early Intervention for Symptomatic Youth at Risk for Bipolar Disorder: A Randomized Trial of Family-Focused Therapy" by David J. Miklowitz, Christopher D. Schneck, Manpreet K. Singh, Dawn O. Taylor, Elizabeth L. George, Victoria E. Cosgrove, Meghan E. Howe, L. Miriam Dickinson, Judy Garber, Kiki D. Chang, (dx.doi.org/10.1016… .2012.10.007) appears in the Journal of the American Academy of Child and Adolescent Psychiatry, Volume 52, Issue 2 (February 2013)
Journal reference: Journal of the American Academy of Child and Adolescent Psychiatry
Provided by Elsevier
- Family therapy helps relieve depression symptoms in bipolar teens Sep 01, 2008 | not rated yet | 0
- Having parents with bipolar disorder associated with increased risk of psychiatric disorders Mar 02, 2009 | not rated yet | 0
- Lawson researcher sings the baby blues Aug 22, 2012 | not rated yet | 0
- 'Wake-Up Pill' Under Study to Treat Patients with Bipolar Disorder Aug 01, 2007 | not rated yet | 0
- Bright light therapy eases bipolar depression for some Jan 03, 2008 | not rated yet | 0
- Motion perception revisited: High Phi effect challenges established motion perception assumptions Apr 23, 2013 | 3 / 5 (2) | 2
- Anything you can do I can do better: Neuromolecular foundations of the superiority illusion (Update) Apr 02, 2013 | 4.5 / 5 (11) | 5
- The visual system as economist: Neural resource allocation in visual adaptation Mar 30, 2013 | 5 / 5 (2) | 9
- Separate lives: Neuronal and organismal lifespans decoupled Mar 27, 2013 | 4.9 / 5 (8) | 0
- Sizing things up: The evolutionary neurobiology of scale invariance Feb 28, 2013 | 4.8 / 5 (10) | 14
Why is zone 1 in liver more prone to ischemic injury?
May 23, 2013 Hi, Is it because around central vein, there is only deoxygenated blood from the vein where as in the periphery there is hepatic artery. Also why...
How can there be villous adenoma in colon, if there are no villi there
May 22, 2013 As title suggest. Thanks :smile:
How can there be a term called "intestinal metaplasia" of stomach
May 21, 2013 Hello everyone, Ok Stomach's normal epithelium is simple columnar, now in intestinal type of adenocarcinoma of stomach it undergoes "intestinal...
Pressure-volume curve: Elastic Recoil Pressure don't make sense
May 18, 2013 From pressure-volume curve of the lung and chest wall (attached photo), I don't understand why would the elastic recoil pressure of the lung is...
If you became brain-dead, would you want them to pull the plug?
May 17, 2013 I'd want the rest of me to stay alive. Sure it's a lousy way to live but it beats being all-the-way dead. Maybe if I make it 20 years they'll...
MRI bill question
May 15, 2013 Dear PFers, The hospital gave us a $12k bill for one MRI (head with contrast). The people I talked to at the hospital tell me that they do not...
- More from Physics Forums - Medical Sciences
More news stories
(Medical Xpress)—Patients with diabetes who are depressed are much more likely to develop episodes of dangerously low blood sugars, or hypoglycemia, than are those who are not depressed, a new study has ...
Psychology & Psychiatry 9 minutes ago | not rated yet | 0 |
A brief visual task can predict IQ, according to a new study. This surprisingly simple exercise measures the brain's unconscious ability to filter out visual movement. The study shows that individuals whose ...
Psychology & Psychiatry 20 hours ago | 4.5 / 5 (10) | 1 |
Nervous about that upcoming job interview? You might want to take steps to reduce your jitters, especially if you are a man.
Psychology & Psychiatry 20 hours ago | 5 / 5 (1) | 0
(Medical Xpress)—Research by U of T Mississauga psychology professor Glenn Schellenberg reveals that two key personality traits – openness-to-experience and conscientiousness—predict better than IQ ...
Psychology & Psychiatry 22 hours ago | 3 / 5 (2) | 1 |
Parents naturally are concerned for their children's safety, particularly when there is news of a child abduction that happens close to home. Finding the balance between emotions and the "teachable moment" as parents talk ...
Psychology & Psychiatry 23 hours ago | not rated yet | 0
(Medical Xpress)—The way Alzheimer's disease is portrayed by advocacy groups and the media is having undue influence on the euthanasia debate, according to a Deakin University nursing ethics professor.
13 minutes ago | not rated yet | 0
Can human genes be patented? That was the question posed by Alan J. Snyder, vice president and associate provost for research and graduate studies at Lehigh, and Lee Kaplan, scientific director of cellular and molecular genetics ...
25 minutes ago | not rated yet | 0
Cardiac study used as source for new guidelines on treating people undergoing coronary artery bypass surgery
Cardiac research from the University of Alberta had serious impact as a source for the American College of Cardiology and the American Heart Association's new guidelines on how to treat patients undergoing coronary artery ...
3 minutes ago | not rated yet | 0
A leading expert in childhood cancer at The University of Nottingham is spearheading a Europe-wide lobby of the European Parliament to try to make it easier for doctors to develop and test new treatments on children and young ...
31 minutes ago | not rated yet | 0
(Medical Xpress)—Regulating the distribution of power in neurons is done by a system that makes the national electric grid look simple by comparison. Each neuron has several thousand mitochondria confined ...
14 hours ago | 4.8 / 5 (6) | 0 |