Harnessing immune cells' adaptability to design an effective HIV vaccine

Recent studies have shown that HIV causes a vigorous and prolonged immune response that eventually leads to the exhaustion of key immune system cells--CD4+ and CD8+ T-cells--that target HIV. These tired cells become less ...

HIV-1 is a genetically diverse collection of viruses, making it a moving target in vaccine development.

HIV tires out the cells that produce virus-fighting proteins known as antibodies, according to a human study that will be published online July 14 in the Journal of Experimental Medicine.

Researchers from Utrecht University, The Netherlands, have developed a model that illustrates how HIV evades the immune system. The study, published July 18th in the open-access journal PLoS Computational Biology, incorp ...

In September 2007, a phase II HIV-1 vaccine trial was abruptly halted when researchers found that the vaccine may have promoted, rather than prevented, HIV infection. A new study by a team of researchers at the Montpellier ...

(Medical Xpress)—The body's most powerful immune cells may have a radical way of catching their prey that could backfire on people who are overweight and others at risk for cancer, diabetes and chronic ...

(HealthDay)—Although spring arrived late this year in parts of the United States, the summer allergy season will still be strong, according to a sinus expert at the University of Alabama at Birmingham.

(Medical Xpress)—A team of Canadian researchers has found that platelets in mice liver collaborate with special types of white blood cells to help capture bacteria. In their paper published in the journal ...

When a strain of bacteria invades a human body, the immune system responds by generating antibodies to neutralize the threat. However, during subsequent infections by a similar bacterium, the immune system ...

Researchers at the University of California, San Diego School of Medicine and colleagues report that the herpes simplex virus type-1 (HSV-1), which affects an estimated 50 to 80 percent of all American adults, exploits an ...

(Medical Xpress)—The ability to predict and implement preventative measures for common diseases, such as diabetes and asthma, even before a baby is born, is one step closer following a breakthrough by University of Sydney ...