Using internet search logs can help identify drug interactions

Using internet search logs can help identify drug interactions
Search logs can be used to inexpensively mine for anonymized signals that may alert authorities to potential drug interactions and add new Web-scale pharmacovigilance capabilities, according to research published online March 6 in the Journal of the American Medical Informatics Association.

(HealthDay)—Search logs can be used to inexpensively mine for anonymized signals that may alert authorities to potential drug interactions and add new Web-scale pharmacovigilance capabilities, according to research published online March 6 in the Journal of the American Medical Informatics Association.

Ryen W. White, Ph.D., of Microsoft Research in Redmond, Wash., and colleagues conducted a large-scale study of Web search log data gathered in 2010 to determine whether early clues about a drug's adverse events might emerge from evaluating search terms.

Specifically, the investigators evaluated whether searches for paroxetine and pravastatin could have been used to predict a of . By examining drug pairs that are known to cause hyperglycemia and those that are not associated with hyperglycemia, they were able to determine that search logs can be used to inexpensively mine for anonymized signals that may improve drug safety surveillance.

"Overall, these findings demonstrate the potential value of the log analysis for identifying drug pairs linked to hyperglycemia and illustrate the generalizability of the method beyond just the pravastatin-paroxetine pairing," the authors write.

More information: Abstract
Full Text (subscription or payment may be required)

add to favorites email to friend print save as pdf

Related Stories

TPN-linked hyperglycemia ups death for non-critically ill

Jan 03, 2013

(HealthDay)—Non-critically ill hospitalized patients who develop hyperglycemia after total parenteral nutrition (TPN) are more than five times more likely to die in the hospital, according to research published ...

Daily exercise doesn't further improve glycemic control

Mar 14, 2012

(HealthDay) -- For individuals with type 2 diabetes, 30 minutes of moderate-intensity endurance exercise once a day or an hour every other day are equally effective for controlling hyperglycemia, according ...

Recommended for you

Study recalculates costs of combination vaccines

11 hours ago

One of the most popular vaccine brands for children may not be the most cost-effective choice. And doctors may be overlooking some cost factors when choosing vaccines, driving the market toward what is actually a more expensive ...

Drug watchdog urges vigilance in cancer drug theft

14 hours ago

Europe's medicine watchdog urged doctors Thursday to be vigilant in administering the cancer drug Herceptin, vials of which had been stolen in Italy and tampered with before being sold back into the supply chain.

Pyridoxine-doxylamine drug safety data lacking

Apr 16, 2014

(Medical Xpress)—The most commonly prescribed drug for pregnant women suffering from morning sickness in their first trimester does not prevent birth defects even though drug safety data says it does, according to research ...

User comments