Lymphoseek approved to help locate lymph nodes

(HealthDay)—The injected imaging drug Lymphoseek (technetium Tc 99m tilmanocept) has been approved by the U.S. Food and Drug Administration to help surgeons locate the lymph nodes among people with breast cancer or melanoma.

The lymph nodes filter lymphatic fluid that flows throughout the body. This fluid may contain if it has passed through diseased tissue, the FDA said in a news release. By surgically examining the lymph nodes, doctors may be able to conclude if cancer has spread.

Lymphoseek is an imaging drug that helps locate the lymph nodes, but it is not a drug, the agency stressed. It's the first lymph-node mapping drug to be approved by the FDA in 30 years.

The drug's safety and effectiveness were established in clinical trials involving 332 people with melanoma or breast cancer. The most common adverse reactions reported were pain and/or irritation at the injection site.

Lymphoseek is marketed by Navidea Biopharmaceuticals, based in Dublin, Ohio.

More information: The FDA has more about this approval.

add to favorites email to friend print save as pdf

Related Stories

New technique may help detect potential breast cancer spread

May 08, 2009

A new phase III clinical trial of early stage breast cancer patients has shown that a molecule designed to home in on nearby lymph nodes is just as accurate as current techniques, but faster, more specific and easier to use.

FDA approves new breast cancer lab test

Jul 17, 2007

The U.S. Food and Drug Administration has approved the first molecular-based laboratory test for detecting whether breast cancer has metastasized.

New signaling pathway linked to breast cancer metastasis

Apr 02, 2012

Lymph nodes help to fight off infections by producing immune cells and filtering foreign materials from the body, such as bacteria or cancer cells. Thus, one of the first places that cancer cells are found when they leave ...

Recommended for you

User comments