New obesity, height genes identified

(Medical Xpress)—Busselton residents and researchers from The University of Western Australia have helped a worldwide scientific collaboration identify new genes associated with height and obesity.

The discovery of four new loci (the specific place on a chromosome where a gene is located) affecting height and seven related to obesity is described in a paper published online today in Nature Genetics.

The paper was authored by more than 300 researchers and is the result of a meta-analysis of dozens of studies around the world collating data from more than 263,000 individuals of European background.

UWA contributors included Research Assistant Professor Gemma Cadby of the Centre for of Health and Disease, who provided analysis of height and weight data from the long-running Busselton .

Dr Cadby said the newly discovered genes represented further pieces in the puzzle as researchers sought to understand the to height and weight.

"They already know of some genes likely to affect height and weight, but these genes only explain a limited amount of the contribution of genetics to these traits," Dr Cadby said. "So a lot of genes still need to be identified, but this is an important step.

"The ultimate goal for is to further the understanding of human diseases and in doing so, to develop new treatments and ways of preventing disease. Actually translating the results of studies such as this into providing intervention, management and treatments for people who are obese is a long way ahead, but in order to do those things you need to understand the genetics of the disease. We have to get this bit of the puzzle before we can move to the next step."

The paper is titled "Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into ."

add to favorites email to friend print save as pdf

Related Stories

Genetic clues for type 2 diabetes

Aug 14, 2012

Busselton residents and researchers from The University of Western Australia have contributed to a worldwide scientific collaboration that has identified new genetic links in the quest to map the biological ...

Wee genes make tall story

Apr 06, 2008

Scientists are beginning to develop a clearer picture of what makes some people stand head and shoulders above the rest. The team of Exeter researchers who last year identified the first common version of a gene influencing ...

Recommended for you

Changes in scores of genes contribute to autism risk

Oct 29, 2014

Small differences in as many as a thousand genes contribute to risk for autism, according to a study led by Mount Sinai researchers and the Autism Sequencing Consortium (ASC), and published today in the journal Nature.

Dozens of genes associated with autism in new research

Oct 29, 2014

Two major genetic studies of autism, led in part by UC San Francisco scientists and involving more than 50 laboratories worldwide, have newly implicated dozens of genes in the disorder. The research shows ...

Genetic link to kidney stones identified

Oct 29, 2014

A new breakthrough could help kidney stone sufferers get an exact diagnosis and specific treatment after genetic links to the condition were identified.

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.