Pot smoking linked to some metabolic changes

April 19, 2013
Pot smoking linked to some metabolic changes
Regularly smoking pot is associated with visceral adiposity and adipose tissue insulin resistance, but not other metabolic changes such as impaired β-cell function or hepatic steatosis, according to a study published online March 25 in Diabetes Care.

(HealthDay)—Regularly smoking pot is associated with visceral adiposity and adipose tissue insulin resistance, but not other metabolic changes such as impaired β-cell function or hepatic steatosis, according to a study published online March 25 in Diabetes Care.

Ranganath Muniyappa, M.D., Ph.D., from the National Institute of Diabetes and Digestive and Kidney Diseases in Bethesda, Md., and colleagues compared abdominal fat depots, intrahepatic fat content, insulin sensitivity, and beta-cell function in 30 cannabis smokers (median of six joints a day for a median of 9.5 years) and 30 matched controls.

The researchers found that, although carbohydrate intake and percent calories from carbohydrates were significantly higher for the cannabis group, total energy intake was similar in both groups. Cannabis smokers had a significantly higher percent abdominal visceral fat (18 versus 12 percent), significantly lower plasma high-density lipoprotein cholesterol (49 versus 55 mg/dL), and a significantly lower adipocyte insulin resistance index and percent suppression during an .

"Chronic cannabis smoking was associated with visceral adiposity and adipose tissue but not with hepatic steatosis, insulin insensitivity, impaired pancreatic β-cell function, or glucose intolerance," Muniyappa and colleagues conclude.

Explore further: Obese adults with excess abdominal fat, insulin resistance may have higher risk of type 2 diabetes

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Insulin sensitivity normally highest after breakfast

October 26, 2012

(HealthDay)—In healthy people without diabetes, glucose responsiveness tends to be higher after breakfast, which may have implications for the design of closed-loop insulin delivery systems for diabetes patients, according ...

Estrogen may improve pathway-selective insulin resistance

February 14, 2013

(HealthDay)—Estrogen treatment at the time of surgical menopause may reverse aspects of pathway-selective insulin resistance in the liver associated with a high-fat diet (HFD) in mice by promoting insulin action on glucose ...

Recommended for you

Which diabetes drug is best?

July 19, 2016

(HealthDay)—No single drug to treat type 2 diabetes stands out from the pack when it comes to reducing the risks of heart disease, stroke or premature death, a new research review finds.

Gut bacteria imbalance increases diabetes risk

July 13, 2016

Currently, scientists think the major contributors to insulin resistance are excess weight and physical inactivity, yet ground-breaking new research by an EU funded European-Chinese team of investigators called MetaHit have ...

Team explores genetic architecture of type 2 diabetes

July 11, 2016

New research from a large international team of scientists offers a more complete picture of the genes responsible for type 2 diabetes, demonstrating that previously identified common alleles shared by many in the world are ...

Normal weight may not protect against diabetes

July 14, 2016

(HealthDay)—Type 2 diabetes has long been considered a disease of the overweight and obese, but a new study challenges that notion. It finds nearly one in five normal-weight people has prediabetes—a condition that can ...

2 comments

Adjust slider to filter visible comments by rank

Display comments: newest first

Canis Maximus
5 / 5 (1) Apr 19, 2013
Will someone please explain:
"significantly lower plasma high-density lipoprotein cholesterol (49 versus 55 mg/dL), and a significantly lower adipocyte insulin resistance index and percent free fatty acids suppression during an oral glucose tolerance test."

for someone not as versed in diabetic etymology?
Mauricio
1 / 5 (1) Apr 19, 2013
http://healthland...-weight/

and this is my personal experience. I know a whole lot of cannabis smokers, and most are skinny, skinnier than the average by far.

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.