Relative proportion of MRSA increasing in S. aureus isolates

April 18, 2013
Relative proportion of MRSA increasing in <i>S. aureus</i> isolates
The relative proportion of methicillin-resistant Staphylococcus aureus is increasing in S. aureus isolates, and methicillin-sensitive S. aureus is becoming increasingly resistant to antibiotics, according to a study published in the April issue of JAMA Dermatology.

(HealthDay)—The relative proportion of methicillin-resistant Staphylococcus aureus (MRSA) is increasing in S. aureus isolates, and methicillin-sensitive S. aureus (MSSA) is becoming increasingly resistant to antibiotics, according to a study published in the April issue of JAMA Dermatology.

Marilyn Zabielinski, M.D., from the University of Miami Miller School of Medicine, and colleagues conducted a using from skin culture isolates from a hospital outpatient dermatology clinic. Three hundred eighty-seven S. aureus isolates were analyzed from Jan. 1, 2005, through June 30, 2011, to determine whether the relative proportions of and MSSA were changing or stable.

The researchers found that the overall relative proportions of MRSA and MSSA were 35.7 and 64.3 percent, respectively. The relative proportions were 33.3 and 66.7 percent, respectively, during the final six months of the study. Compared with the period from Jan. 1, 2005, through Dec. 31, 2007, the relative proportion of MRSA was significantly higher for the period from Jan. 1, 2008, through Dec. 31, 2010 (45.3 versus 28.3 percent). The sensitivity of MRSA to ciprofloxacin increased during the study period, while MSSA became increasingly resistant to ciprofloxacin, clindamycin, sulfate, and trimethoprim-sulfamethoxazole.

"Consistent with national data, the relative proportion of MRSA in this outpatient dermatology clinic in Miami has risen," the authors write. "In addition to the rise in proportion of MRSA in our outpatient dermatology clinic, we observed a notable trend that MSSA is becoming more resistant to many antibiotics."

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Staph sepsis increases mortality in preterm infants

March 12, 2012

(HealthDay) -- Only about 1 percent of very low birth weight (VLBW) infants develop methicillin-resistant Staphylococcus aureus (MRSA) infections, and the morbidity and mortality are similar to that seen in infants with methicillin-susceptible ...

MRSA skin infections up, linked to furunculosis

July 27, 2012

(HealthDay) -- The incidence of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) in the United States is increasing and is associated with follicular infection, most commonly folliculitis followed ...

Superbug MRSA identified in US wastewater treatment plants

November 5, 2012

A team led by researchers at the University of Maryland School of Public Health has found that the "superbug" methicillin-resistant Staphylococcus aureus (MRSA) is prevalent at several U.S. wastewater treatment plants (WWTPs). ...

Recommended for you

Experimental MERS vaccine shows promise in animal studies

July 28, 2015

A two-step regimen of experimental vaccines against Middle East respiratory syndrome (MERS) prompted immune responses in mice and rhesus macaques, report National Institutes of Health scientists who designed the vaccines. ...

Can social isolation fuel epidemics?

July 21, 2015

Conventional wisdom has it that the more people stay within their own social groups and avoid others, the less likely it is small disease outbreaks turn into full-blown epidemics. But the conventional wisdom is wrong, according ...

Lack of knowledge on animal disease leaves humans at risk

July 20, 2015

Researchers from the University of Sydney have painted the most detailed picture to date of major infectious diseases shared between wildlife and livestock, and found a huge gap in knowledge about diseases which could spread ...

IBD genetically similar in Europeans and non-Europeans

July 20, 2015

The first genetic study of inflammatory bowel disease (IBD) to include individuals from diverse populations has shown that the regions of the genome underlying the disease are consistent around the world. This study, conducted ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.