Study shows COPD is associated with significant and persistent pain

May 21, 2013

Chronic obstructive pulmonary disease (COPD) is primarily associated with the respiratory symptoms that are its hallmark, but in fact, patients who struggle with the disease also experience significant amounts of chronic pain. A new study conducted by researchers in Pennsylvania and New Mexico estimates the degree of pain suffered by these patients to be close to that experienced by patients with osteoarthritis and rheumatoid arthritis.

The research results will be presented at the ATS 2013 International Conference.

"Several studies have found high rates of use among COPD patients, and pain has also been an important determinant of overall health status and quality of life in COPD," said study lead author Melissa Roberts, MS, senior research associate at the Lovelace Clinic Foundation in Albuquerque and a doctoral candidate at the University of New Mexico College of Pharmacy.

"In prior studies, we had observed increased narcotic and non-narcotic pain medication use among individuals with COPD and were interested in whether this was because the COPD population tends to be older and have more comorbidities, or whether there might be an association between COPD and pain above and beyond what age and comorbidities might explain," she said. "In this study, we chose to compare in individuals with COPD and individuals with that similarly affect multiple body systems."

The used data gathered from 7,952 COPD patients and 15,904 non-COPD patients over the age of 40 who were enrolled in a managed care system in the southwestern United States from 2006 through 2010. The presence of pain was determined by pain-associated diagnosis codes, the use of pain therapy and outpatient prescription claims for pain medication, and recurrent therapy and prescriptions were considered evidence of chronic pain.

The researchers found that compared to those with non-COPD chronic disease, a greater number of patients with COPD had some indication of chronic pain and use of pain-related medications, including both short-acting and long-acting opioids. However, chronic pain was not associated with lung function impairment among the study patients, suggesting the causes of pain are not directly associated with airflow obstruction. The only subset of patients with greater prevalence of chronic pain and use of pain medication were patients with either rheumatoid arthritis or osteoarthritis.

"We found the prevalence of chronic pain among adults with chronic disease to be almost twice as high as among individuals without chronic disease," Ms. Roberts noted. "Among those with chronic disease, individuals with COPD were similar to those with or osteoarthritis in their experience of pain, but with even greater use of opioids."

An investigation of the incremental costs associated with chronic pain is under way, she noted.

"The socioeconomic impact of chronic pain on with COPD is also an understudied issue, and many health care organizations conduct management programs for which significantly impact quality of life," Ms. Roberts said. "Among individuals with COPD, pain may be having a marked impact on their quality of life, potentially as much as their respiratory disease, and contributing significantly to their cost of care."

Explore further: Pain training for primary care providers

Related Stories

Pain training for primary care providers

March 5, 2013

Patients who experience chronic pain may experience improvement in symptoms if their primary care providers are specifically trained in multiple aspects of pain, including emotional consequences.

Antibiotic therapy appears beneficial for patients with COPD

May 21, 2013

Extended use of a common antibiotic may prolong the time between hospitalizations for patients suffering from chronic obstructive pulmonary disease (COPD), according to a post-hoc analysis of a multicenter study which compared ...

Inflammation is associated with depression in COPD patients

May 21, 2013

Depression is common in patients with chronic obstructive pulmonary disease (COPD) and has been linked with disease severity and impaired quality of life. Now, for the first time, researchers at the University of Pittsburgh ...

Recommended for you

Monkeys in Asia harbor virus from humans, other species

November 19, 2015

When it comes to spreading viruses, bats are thought to be among the worst. Now a new study of nearly 900 nonhuman primates in Bangladesh and Cambodia shows that macaques harbor more diverse astroviruses, which can cause ...

One-step test for hepatitis C virus infection developed

November 14, 2015

UC Irvine Health researchers have developed a cost-effective one-step test that screens, detects and confirms hepatitis C virus (HCV) infections. Dr. Ke-Qin Hu, director of hepatology services, will present findings at the ...

Computer model reveals deadly route of Ebola outbreak

November 10, 2015

Using a novel statistical model, a research team led by Columbia University's Mailman School of Public Health mapped the spread of the 2014-2015 Ebola outbreak in Sierra Leone, providing the most detailed picture to date ...


Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.