Free fatty acids linked to cardiac risk in late adulthood

Free fatty acids linked to cardiac risk in late adulthood
Blood levels of free fatty acids are associated with insulin resistance during young adulthood and cardiovascular risk factors in later adulthood, according to a study published online May 13 in Diabetes.

(HealthDay)—Blood levels of free fatty acids are associated with insulin resistance during young adulthood and cardiovascular risk factors in later adulthood, according to a study published online May 13 in Diabetes.

Brigitte I. Frohnert, M.D., Ph.D., from the University of Minnesota in Minneapolis, and colleagues examined the relationship of serum total to adiposity, , and cardiovascular risk factors in 207 individuals at 15 and 22 years of age, as well as their parents.

The researchers found that, while there was no significant association between free fatty acids and insulin resistance at 15 years of age, the association became significant at 22 years of age, and free fatty acids at 15 years of age estimated insulin resistance at 22 years of age. In the parents there was a significant association between free fatty acids and , percent body fat, , low-density lipoprotein cholesterol, and insulin resistance, although adjusting for body mass index attenuated all associations except insulin resistance. Most associations with parents were stronger at 22 years of age than at 15 years of age.

"This study finds that free fatty acids [are] associated with insulin resistance starting in young adulthood," Frohnert and colleagues conclude. "The relation between free fatty acids and cardiovascular risk factors does not become significant until later adulthood."

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Gene variants link to insulin resistance based on diet

Apr 28, 2013

(HealthDay)—Variants of insulin receptor substrate 1 (IRS1) are associated with insulin resistance and metabolic syndrome, but only under particular dietary conditions, according to a study published online ...

Metabolites linked to insulin resistance in normoglycemia

Apr 23, 2012

(HealthDay) -- Twenty metabolites, including amino acids, intermediates in glucose synthesis, ketone bodies, and fatty acids, are associated with insulin resistance, according to a study published online April ...

Pot smoking linked to some metabolic changes

Apr 19, 2013

(HealthDay)—Regularly smoking pot is associated with visceral adiposity and adipose tissue insulin resistance, but not other metabolic changes such as impaired β-cell function or hepatic steatosis, according ...

n-3 fatty acids no benefit for high-risk cardio patients

May 09, 2013

(HealthDay)—For patients with multiple cardiovascular risk factors or atherosclerotic vascular disease who have not had a myocardial infarction, daily treatment with n-3 fatty acids does not reduce cardiovascular ...

Recommended for you

Study: Removing clot helps limit stroke disability

Dec 17, 2014

For the first time in several decades, a new treatment has been shown to limit the damage from a common type of stroke. Researchers in the Netherlands found that mechanically removing a clot in addition to using a clot-busting ...

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.