Fertility preservation guidelines for cancer patients reviewed

Fertility preservation guidelines for cancer patients reviewed
No major, substantive revisions were necessary, but clarifications were added to update the American Society of Clinical Oncology guidelines on fertility preservation for children and adults with cancer, according to a report published online May 28 in the Journal of Clinical Oncology.

(HealthDay)—No major, substantive revisions were necessary, but clarifications were added to update the American Society of Clinical Oncology (ASCO) guidelines on fertility preservation for children and adults with cancer, according to a report published online May 28 in the Journal of Clinical Oncology.

Alison W. Loren, M.D., of the University of Pennsylvania in Philadelphia, and colleagues used MEDLINE and the Cochrane Collaboration Library to perform a systematic review of the published from March 2006 through January 2013. An Update Panel reviewed the evidence and drafted updates to the previous ASCO guidelines on fertility preservation in cancer patients.

The researchers found 222 new publications, including 18 , as well as observational studies, cohort studies, and case series or case reports, that met the inclusion criteria. After reviewing the evidence, the panel made minor revisions to the guidelines and clarified the language. should discuss the possibility of infertility with adults of reproductive age, or the parents or guardians of children and adolescents, and address fertility preservation as early as possible, before treatment for cancer. Cancer patients should be referred to reproductive specialists for fertility preservation. Cryopreservation of oocytes, sperm, and embryos is considered standard practice.

"After a systematic review and analysis of the literature for the preservation of fertility for patients with cancer, the Update Panel concluded that there was no new evidence compelling enough to warrant substantial changes to any of the . However, minor adjustments were made to reflect progress in the field (e.g., oocyte cryopreservation is no longer investigational)," the authors write. "Information has been added to address role of psychosocial providers, fertility preservation concerns, and options for children and adolescents with cancer, as well as considerations for patients receiving targeted and biologic therapies."

More information: Abstract
Full Text

add to favorites email to friend print save as pdf

Related Stories

Recommended for you

The fine line between breast cancer and normal tissues

11 hours ago

Up to 40 percent of patients undergoing breast cancer surgery require additional operations because surgeons may fail to remove all the cancerous tissue in the initial operation. However, researchers at Brigham ...

Pancreatic cancer risk not higher with diabetes Rx DPP-4i

12 hours ago

(HealthDay)—There is no increased short-term pancreatic cancer risk with dipeptidyl-peptidase-4 inhibitors (DPP-4i) compared to sulfonylureas (SU) and thiazolidinediones (TZD) for glycemic control, according ...

Good bowel cleansing is key for high-quality colonoscopy

15 hours ago

The success of a colonoscopy is closely linked to good bowel preparation, with poor bowel prep often resulting in missed precancerous lesions, according to new consensus guidelines released by the U.S. Multi-Society Task ...

New rules for anticancer vaccines

16 hours ago

Scientists have found a way to find the proverbial needle in the cancer antigen haystack, according to a report published in The Journal of Experimental Medicine.

User comments