Local vancomycin reduces infections in cervical fusion

Local vancomycin reduces infections in cervical fusion
The local application of prophylactic vancomycin significantly reduces the risk of surgical site infections in patients undergoing multilevel posterior cervical-instrumented fusions for cervical spondylotic myelopathy, according to a study published in the June 15 issue of Spine.

(HealthDay)—The local application of prophylactic vancomycin significantly reduces the risk of surgical site infections in patients undergoing multilevel posterior cervical-instrumented fusions for cervical spondylotic myelopathy (CSM), according to a study published in the June 15 issue of Spine.

Cyrus Caroom, M.D., from Scott & White Healthcare in Temple, Texas, and colleagues assessed prospectively collected data from 112 patients undergoing multilevel posterior decompression and instrumentation for CSM by a single surgeon (2003 to 2011). The authors sought to compare outcomes for treated without the use of vancomycin powder (72 participants) with outcomes for those treated after the initiation of vancomycin powder prophylaxis (40 participants).

The researchers found that the groups were statistically similar with regard to age, body mass index, comorbidities, estimated blood loss, and operative time. However, there was a significant decrease in rate in the intervention group (0 percent) compared with the control group (15 percent). The use of vancomycin powder was not associated with adverse events.

"This study supports the growing body of evidence that powder placed in the wound can reduce the incidence of postoperative wound infections, and is the first that addresses this specific population," the authors write.

The study was funded by grants from Globus, Medtronic, and SpineSmith.

More information: Abstract
Full Text (subscription or payment may be required)

add to favorites email to friend print save as pdf

Related Stories

Instrumented spinal fusion method impacts infection rate

May 21, 2012

(HealthDay) -- For patients who undergo instrumented spinal fusion, the rates of infection are higher among those who receive posterior lumbar interbody fusion compared with those who receive posterior or ...

Less commonly prescribed antibiotic may be better

Aug 16, 2012

The antibiotic most commonly prescribed to treat bloodstream infections in dialysis patients may not always be the best choice, according to a study appearing in an upcoming issue of the Journal of the American Society of ...

Recommended for you

Mali announces new Ebola case

19 hours ago

Mali announced Saturday a new case of Ebola in a man who is fighting for his life in an intensive care unit in the capital Bamako.

Plague outbreak kills 40 in Madagascar: WHO

19 hours ago

An outbreak of plague has killed 40 people in Madagascar, the World Health Organization said, warning that the disease could spread rapidly in the country's densely populated capital Antananarivo.

UN chief: Ebola cases in Mali a 'deep concern'

Nov 21, 2014

The United Nations chief warned Friday that Ebola may be easing in part of West Africa but is still hitting hard in other areas and outpacing the international response.

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.