Drinking alcohol during pregnancy affects learning and memory function in offspring?

Drinking alcohol during pregnancy affects learning and memory function in offspring?
A large number of hippocampal neurons were stained with cyclin-dependent kinase 5 in the offspring from the ethanol-treated group (immunofluorescence, × 400). Credit: Neural Regeneration Research

Maternal alcohol consumption during pregnancy has detrimental effects on fetal central nervous system development.

Maternal prior to and during pregnancy significantly affects cognitive functions in offspring, which may be related to changes in cyclin-dependent kinase 5 because it is associated with modulation of synaptic plasticity and impaired learning and memory. Prof. Ruiling Zhang and team from Xinxiang Medical University explored the correlation between cyclin-dependent kinase 5 expression in the hippocampus and neurological impairments following prenatal ethanol exposure, and found that prenatal ethanol exposure could affect cyclin-dependent kinase 5 and its activator p35 in the hippocampus of offspring rats.

These findings, which reported in the Neural Regeneration Research (Vol. 8, No. 18, 2013), propose new insights into the mechanisms underlying the role of ethanol exposure in injuries, and provide a new strategy for treating the consequences of prenatal ethanol exposure.

Provided by Neural Regeneration Research

not rated yet
add to favorites email to friend print save as pdf

Related Stories

Alcohol exposure in the womb affects 'teenage' booze behavior

Jan 15, 2009

Rats whose mothers were fed alcohol during pregnancy are more attracted to the smell of liquor during puberty. Researchers writing in BioMed Central's open access journal Behavioral and Brain Functions have shown that rats e ...

Alcoholic fly larvae need fix for learning

Nov 29, 2012

Fly larvae fed on alcohol-spiked food for a period of days grow dependent on those spirits for learning. The findings, reported in Current Biology on November 29, show how overuse of alcohol can produce lastin ...

Recommended for you

Tooth loss linked to slowing mind and body

12 hours ago

The memory and walking speeds of adults who have lost all of their teeth decline more rapidly than in those who still have some of their own teeth, finds new UCL research.

Hot flashes linked to increased risk of hip fracture

16 hours ago

Women who experience moderate to severe hot flashes and night sweats during menopause tend to have lower bone mineral density and higher rates of hip fracture than peers who do not have menopausal symptoms, according to a ...

Core hospital care team members may surprise you

16 hours ago

Doctors and nurses are traditionally thought to be the primary caretakers of patients in a typical hospital setting. But according to a study at the burn center intensive care unit at Loyola University Health System, three ...

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.