Drinking alcohol during pregnancy affects learning and memory function in offspring?

Drinking alcohol during pregnancy affects learning and memory function in offspring?
A large number of hippocampal neurons were stained with cyclin-dependent kinase 5 in the offspring from the ethanol-treated group (immunofluorescence, × 400). Credit: Neural Regeneration Research

Maternal alcohol consumption during pregnancy has detrimental effects on fetal central nervous system development.

Maternal prior to and during pregnancy significantly affects cognitive functions in offspring, which may be related to changes in cyclin-dependent kinase 5 because it is associated with modulation of synaptic plasticity and impaired learning and memory. Prof. Ruiling Zhang and team from Xinxiang Medical University explored the correlation between cyclin-dependent kinase 5 expression in the hippocampus and neurological impairments following prenatal ethanol exposure, and found that prenatal ethanol exposure could affect cyclin-dependent kinase 5 and its activator p35 in the hippocampus of offspring rats.

These findings, which reported in the Neural Regeneration Research (Vol. 8, No. 18, 2013), propose new insights into the mechanisms underlying the role of ethanol exposure in injuries, and provide a new strategy for treating the consequences of prenatal ethanol exposure.

Provided by Neural Regeneration Research

not rated yet
add to favorites email to friend print save as pdf

Related Stories

Alcohol exposure in the womb affects 'teenage' booze behavior

Jan 15, 2009

Rats whose mothers were fed alcohol during pregnancy are more attracted to the smell of liquor during puberty. Researchers writing in BioMed Central's open access journal Behavioral and Brain Functions have shown that rats e ...

Alcoholic fly larvae need fix for learning

Nov 29, 2012

Fly larvae fed on alcohol-spiked food for a period of days grow dependent on those spirits for learning. The findings, reported in Current Biology on November 29, show how overuse of alcohol can produce lastin ...

Recommended for you

Older adults are at risk of financial abuse

4 hours ago

Nearly one in every twenty elderly American adults is being financially exploited – often by their own family members. This burgeoning public health crisis especially affects poor and black people. It merits the scrutiny ...

Medical internet could transform health care

4 hours ago

The medical Internet is not yet here, but the widespread availability of electronic medical records and enhanced data-storage capabilities are pushing it closer to reality. As now envisioned, this new cyberspace ...

User comments