Chemoprophylaxis found to be safe after spine trauma surgery

Chemoprophylaxis found to be safe after spine trauma surgery
Thromboembolic chemoprophylaxis seems to be safe and efficacious in at-risk trauma patients having spinal stabilization surgery, according to a retrospective review published in the July 15 issue of Spine.

(HealthDay)—Thromboembolic chemoprophylaxis seems to be safe and efficacious in at-risk trauma patients having spinal stabilization surgery, according to a retrospective review published in the July 15 issue of Spine.

Lloydine J. Jacobs, M.D., from the University of Pittsburgh Medical Center, and colleagues retrospectively reviewed cases of 227 patients with spinal trauma who underwent surgical stabilization (2009 and 2010) at a single level 1 trauma center. Patients who underwent solely decompressive procedures, non-instrumented fusions, or were excluded.

The researchers found that 56 patients were not treated with chemoprophylaxis and 171 were treated. Postoperative thromboembolism was seen in eight patients in the untreated group (14.3 percent) and 12 patients in the treated group (7 percent; P = 0.096), while occurred in one and four patients, respectively. One untreated patient and 5.3 percent of the treated group required surgical irrigation and debridement for wound drainage. No epidural hematomas were seen in either group. More spinal levels were fused (P = 0.46) and significantly higher injury severity scores (P = 0.001) and longer hospitalizations (P = 0.018) were seen in the treated group. Significantly higher body mass indexes (P = 0.01), injury severity scores (P = 0.001), number of spinal levels fused (P = 0.004), incidence of neurological deficits (P = 0.001), and longer hospitalizations (P = 0.16) were seen in patients who developed postoperative thromboembolism.

"The use of appears to be safe in at-risk patients in the immediate postoperative period after spinal trauma surgery," the authors write.

More information: Abstract
Full Text (subscription or payment may be required)

add to favorites email to friend print save as pdf

Related Stories

Study examines opiate use in orthopedic trauma patients

Jun 27, 2013

(HealthDay)—Orthopedic trauma patients with isolated musculoskeletal injuries are significantly more likely than the general population to have used prescription opiates prior to injury, and pre-injury ...

Epidural during/Post spine surgery gives better outcomes

Jul 17, 2013

(HealthDay)—In patients undergoing reconstructive spine surgery, combined epidural and general anesthesia results in better pain control and other outcomes compared with general anesthesia plus narcotics, ...

Fusion rate up for lumbar spinal stenosis, 2004 to 2009

Jun 13, 2013

(HealthDay)—For patients hospitalized for lumbar spinal stenosis (LSS), the rate of fusions significantly increased and the rate of decompressions significantly decreased from 2004 to 2009 in the United ...

Radiography unnecessary after spinal fusion surgery

Sep 17, 2012

(HealthDay)—In patients who have undergone spinal fusion surgery with intraoperative fluoroscopic guidance and have no postoperative problems, postoperative radiographs do not provide additional clinical ...

Recommended for you

Surgery for spinal metastasis up from 2000 to 2009 in US

11 hours ago

(HealthDay)—From 2000 to 2009 there was an increase in surgical treatment for spinal metastasis in the United States, which was accompanied by increased complication rates and costs, according to a study ...

User comments