Exercise-induced improvements in glycemic control and type 2 diabetes

Exercise-induced improvements in glycemic control are dependent on the pre-training glycemic level, and although moderate-intensity aerobic exercise can improve glycemic control, individuals with ambient hyperglycemia (high blood glucose) are more likely to be nonresponders, according to a research letter by Thomas P. J. Solomon, Ph.D. of the Centre of Inflammation and Metabolism, Copenhagen, Denmark, and colleagues.

A total of 105 older (average age 61 years), overweight or obese individuals with impaired glucose tolerance or type 2 diabetes mellitus (T2DM) participated in a 12-to 16-week period of aerobic exercise training. Researchers measured the participants' , aerobic fitness, and glycemic control, and assessed the relationships between pre-intervention variables and intervention-induced changes.

Average change in body weight, whole-body fat, fasting and 2-hour (OGTT) were significantly improved following exercise training. However, researchers found that aerobic exercise-induced improvements in glycemic control were reduced by ambient hyperglycemia, particularly in participants with T2DM.

"The clinical relevance of these new findings is paramount and highlights the need to understand the metabolic "nonresponder." Because chronic hyperglycemia…potentially predicts a poor therapeutic effect of aerobic exercise on glycemic control and fitness, using exercise to treat patients with poorly controlled T2DM may have limited chances of a successful outcome," the study concludes.

More information: JAMA Intern Med. Published online July 1, 2013. doi:10.1001/jamainternmed.2013.7783

add to favorites email to friend print save as pdf

Related Stories

Exercise improves quality of life in type 2 diabetes

Mar 19, 2013

(HealthDay)—For people with type 2 diabetes mellitus (T2DM), a nine-month aerobic and resistance training program significantly improves quality of life (QOL) compared with no exercise, according to research ...

Recommended for you

AMA examines economic impact of physicians

2 hours ago

(HealthDay)—Physicians who mainly engage in patient care contribute a total of $1.6 trillion in economic output, according to the American Medical Association (AMA)'s Economic Impact Study.

Less-schooled whites lose longevity, study finds

2 hours ago

Barbara Gentry slowly shifts her heavy frame out of a chair and uses a walker to move the dozen feet to a chair not far from the pool table at the Buford Senior Center. Her hair is white and a cough sometimes interrupts her ...

How to keep your fitness goals on track

2 hours ago

(HealthDay)—The New Year's resolutions many made to get fit have stalled by now. And one expert thinks that's because many people set their goals too high.

Suddenly health insurance is not for sale

Apr 18, 2014

(HealthDay)— Darlene Tucker, an independent insurance broker in Scotts Hill, Tenn., says health insurers in her area aren't selling policies year-round anymore.

User comments