Exercise-induced improvements in glycemic control and type 2 diabetes

Exercise-induced improvements in glycemic control are dependent on the pre-training glycemic level, and although moderate-intensity aerobic exercise can improve glycemic control, individuals with ambient hyperglycemia (high blood glucose) are more likely to be nonresponders, according to a research letter by Thomas P. J. Solomon, Ph.D. of the Centre of Inflammation and Metabolism, Copenhagen, Denmark, and colleagues.

A total of 105 older (average age 61 years), overweight or obese individuals with impaired glucose tolerance or type 2 diabetes mellitus (T2DM) participated in a 12-to 16-week period of aerobic exercise training. Researchers measured the participants' , aerobic fitness, and glycemic control, and assessed the relationships between pre-intervention variables and intervention-induced changes.

Average change in body weight, whole-body fat, fasting and 2-hour (OGTT) were significantly improved following exercise training. However, researchers found that aerobic exercise-induced improvements in glycemic control were reduced by ambient hyperglycemia, particularly in participants with T2DM.

"The clinical relevance of these new findings is paramount and highlights the need to understand the metabolic "nonresponder." Because chronic hyperglycemia…potentially predicts a poor therapeutic effect of aerobic exercise on glycemic control and fitness, using exercise to treat patients with poorly controlled T2DM may have limited chances of a successful outcome," the study concludes.

More information: JAMA Intern Med. Published online July 1, 2013. doi:10.1001/jamainternmed.2013.7783

add to favorites email to friend print save as pdf

Related Stories

Exercise improves quality of life in type 2 diabetes

Mar 19, 2013

(HealthDay)—For people with type 2 diabetes mellitus (T2DM), a nine-month aerobic and resistance training program significantly improves quality of life (QOL) compared with no exercise, according to research ...

Recommended for you

Health care organizations see value of telemedicine

4 hours ago

(HealthDay)—Health care organizations are developing and implementing telemedicine programs, although many have yet to receive reimbursement, according to a report published by Foley & Lardner.

Before you go... are you in denial about death?

11 hours ago

For most of us, death conjures up strong feelings. We project all kinds of fears onto it. We worry about it, dismiss it, laugh it off, push it aside or don't think about it at all. Until we have to. Of course, ...

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.