Lifesaving HIV treatment could reach millions more people following landmark study

Millions more people could get access to life-saving HIV drug therapy, following a landmark study led by Australian researchers based at the Kirby Institute at the University of New South Wales (UNSW).

The researchers have found a lower daily dose of an important HIV drug therapy is safe and as effective in suppressing the virus as the standard recommended dose.

The findings have been presented at the International AIDS Society Conference in Kuala Lumpur, Malaysia.

"This has the potential to affect the treatment of millions of HIV positive people," says UNSW Professor Sean Emery, the protocol chairperson of the study, known as ENCORE1 and Head of the Therapeutic and Vaccine Research Program at the Kirby Institute.

"A reduced daily dose should translate into a lower cost of treatment and permit more effective and efficient use of . Essentially, more people could receive this life-saving treatment for the same amount of funding."

HIV-positive people from 13 countries in Africa, Asia, Australia, Europe and Latin America took part in the trial. Half these people took two-thirds of the current standard daily dose of the antiretroviral (ART) efavirenz, a commonly used treatment for HIV; the other half took the standard daily dose. The 630 participants were observed regularly for a year. The results indicate that a reduction in daily dose of one third is both safe and effective compared to the higher dose currently recommended for people with HIV infection.

add to favorites email to friend print save as pdf

Related Stories

UN urges Asia to ditch punitive laws to fight AIDS (Update)

Jul 01, 2013

(AP)—U.N. health officials urged Asian governments Monday to get rid of what they say are punitive laws that hinder the battle against HIV and AIDS by discriminating against high-risk groups and deterring them from seeking ...

Food insecurity linked to HIV-treated drug users' deaths

May 31, 2013

Food insecurity increases the risk of death among injection drug users living with HIV/AIDS even when they are receiving life-prolonging antiretroviral therapy (ART), according to a new study involving Simon Fraser University.

Recommended for you

Preventing one case of HIV saves over $225K, study shows

Feb 27, 2015

How much money would be saved if one high-risk person was prevented from contracting HIV in the United States? A new study led by a researcher at Weill Cornell Medical College and published online Feb. 24 in Medical Care, answer ...

Research captures transient details of HIV genome packaging

Feb 27, 2015

Once HIV-1 has hijacked a host cell to make copies of its own RNA genome and viral proteins, it must assemble these components into new virus particles. The orchestration of this intricate assembly process falls to a viral ...

Could an HIV drug beat strep throat, flesh-eating bacteria?

Feb 25, 2015

With antibiotic resistance on the rise, scientists are looking for innovative ways to combat bacterial infections. The pathogen that causes conditions from strep throat to flesh-eating disease is among them, but scientists ...

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.