Spondylolisthesis sx improves pediatric health related-QOL

Spondylolisthesis sx improves pediatric health related-QOL
In pediatric patients with high-grade spondylolisthesis, health-related quality of life (HRQOL) improves significantly after surgery, especially in patients with low baseline HRQOL scores, according to a study published in the July issue of The Spine Journal.

(HealthDay)—In pediatric patients with high-grade spondylolisthesis, health-related quality of life (HRQOL) improves significantly after surgery, especially in patients with low baseline HRQOL scores, according to a study published in the July issue of The Spine Journal.

Étienne Bourassa-Moreau, M.D., from the University of Montreal, and colleagues conducted an observational case series study involving 28 with high-grade (23 managed surgically and five managed nonsurgically) for a minimum of two years to describe changes in HRQOL. Neurologic exams and radiographic evaluations of slip grade were conducted, and self-reported Scoliosis Research Society questionnaires (SRS-22) were administered at baseline and follow-up.

The researchers found that, at baseline and last follow-up, the total SRS-22 scores were 3.31 ± 0.50 and 4.26 ± 0.50, respectively, for (P < 0.001). The corresponding scores for nonsurgical patients were 4.12 ± 0.16 and 4.14 ± 0.38 (P = 0.854). There was a significant correlation between improvement in the SRS-22 score and low baseline value of SRS-22. In the nonsurgical patients there was no neurologic or slip deterioration during the follow-up.

"This article demonstrated that the HRQOL significantly improves after surgery in pediatric high-grade spondylolisthesis, especially in patients with low baseline HRQOL scores," the authors write. "Nonsurgical treatment with observation of high-grade spondylolisthesis can be considered in patients with near-normal baseline HRQOL, no evidence of progression, and no neurologic impairment."

Several authors disclosed to the medical device and technology industries.

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Scoliosis surgery improves adolescents' quality of life

date Nov 02, 2012

(HealthDay)—Surgical treatment of adolescent idiopathic scoliosis (AIS) significantly improves quality of life (QOL), according to research published online Oct. 22 in the Journal of Spinal Disorders & ...

QoL up for live liver donors versus general population

date Nov 06, 2012

(HealthDay)—Living liver donors from Japan have higher health-related quality of life (HRQOL) than the Japanese norm population, according to a study published in the November issue of Liver Transplantation.

Recommended for you

'Ebola will return', veteran scientist warns

date 4 hours ago

Congolese expert Jean-Jacques Muyembe may be little known to the public, but he has been one of the world's top Ebola investigators since the first epidemic erupted in central Africa in 1976.

Score IDs patients with upper extremity DVT at low risk

date 19 hours ago

(HealthDay)—For patients with upper-extremity deep vein thrombosis (DVT), six easily available factors can be used to create a score that identifies those at low risk of adverse events during the first ...

Combined drug treatment combats kidney disease

date May 29, 2015

A recent discovery by drug researchers whereby coupling specific cell membrane receptors has altered kidney cell function has triggered a re-think of how to treat chronic kidney disease (CKD) more effectively.

Active substance targeting dreaded hospital germs

date May 29, 2015

In the German Center for Infection Research (DZIF), scientists have conducted clinical studies on an active substance against the dreaded hospital pathogen Staphylococcus aureus: a highly effective protein from bacteriophages ...

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.