New techniques use lasers, LEDs, and optics to 'see' under the skin

July 25, 2013

Impressive examples of new non-invasive optical techniques using lasers, light-emitting diodes (LEDs), and spectroscopic methods to probe and render images from beneath the surface of the skin are featured in a newly completed special section in the Journal of Biomedical Optics published by SPIE, the international society for optics and photonics. The techniques may be used in a wide variety of medical and cosmetic applications such as treating burns, identifying cancer, or speeding the healing of wounds.

"The skin is the biggest organ of the body, and serves as its barrier to the environment," noted Special Section Guest Editor Jürgen Lademann of the Charité-Universitätsmedizin Berlin. "It provides protection against , keeps micro-organisms from invading the body, and responds sensitively to external stimuli. As a , the skin is an essential means of interpersonal communication."

Because they are easily accessible, the skin barrier and the underlying living cell layers are ideal subjects for investigation by optical and spectroscopic methods using light-based technologies that work from outside the body, Lademann said. Technologies such as fluorescence, reflectance, laser scanning microscopy, and Raman spectroscopy enable identification of tissues and fluids based on how their specific physical and chemical properties cause them to react to different wavelengths of light.

Optical imaging methods are becoming increasingly popular in the field of pharmacology, specifically for investigating the penetration of topically applied substances into and through the skin barrier. Other uses are imaging blood flow and analysis of the wound healing processes.

Explore further: Too much of a good thing? Too many 'healing' cells delays wound healing

More information: biomedicaloptics.spiedigitallibrary.org/issue.aspx?journalid=93&issueid=25400

Related Stories

Recommended for you

Key regulator of bone development identified

December 8, 2016

Loss of a key protein leads to defects in skeletal development including reduced bone density and a shortening of the fingers and toes—a condition known as brachydactyly. The discovery was made by researchers at Penn State ...

TET proteins drive early neurogenesis

December 7, 2016

The fate of stem cells is determined by series of choices that sequentially narrow their available options until stem cells' offspring have found their station and purpose in the body. Their decisions are guided in part by ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.