Depression modifies type A behavior, mortality link in T1DM

Depression modifies type A behavior, mortality link in T1DM
For individuals with type 1 diabetes, type A personality is associated with lower all-cause mortality, with the correlation modified by depressive symptomatology, according to a study published online July 8 in Diabetes Care.

(HealthDay)—For individuals with type 1 diabetes, type A personality is associated with lower all-cause mortality, with the correlation modified by depressive symptomatology, according to a study published online July 8 in Diabetes Care.

Catherine E. Fickley, M.P.H., from the University of Pittsburgh, and colleagues used data from 22 years of follow-up from the Pittsburgh Epidemiology of Diabetes Complications study involving 506 participants with to examine whether type A behavior predicts all-cause mortality and incident (CAD). At baseline in 1986 to 1988, participants completed the Bortner Rating Scale (to assess type A behavior) and the Beck Depression Inventory (BDI).

During follow-up, the researchers identified 128 deaths (25.3 percent). There was a significant inverse correlation between Bortner scores and all-cause mortality in univariate analysis, which persisted after adjustment for multiple confounders, including age, sex, duration, glycated hemoglobin, education, smoking, , and physical activity. The correlation was attenuated after adjustment for BDI scores; the protective effect was limited among those with lower BDI scores (lower three quartiles; P = 0.07), but no effect was observed in those with higher BDI scores (P = 0.97). A borderline association was observed for Bortner scores with incident CAD (P = 0.09).

"Those with higher type A behavior have lower all-cause mortality in our type 1 diabetic population, an effect that interacts with depressive symptomatology such that it is only operative in those with low BDI scores," the authors write. "Further research should focus on understanding this interaction."

More information: Abstract
Full Text (subscription or payment may be required)

add to favorites email to friend print save as pdf

Related Stories

Women with RA report lower sexual function

Oct 17, 2012

(HealthDay)—Rheumatoid arthritis (RA) has negative effects on sexual function in women, with depressive symptoms and disease severity linked to the degree of sexual dysfunction, according to a study published ...

Depression, antidepressant use linked to future CVD risk

Jun 10, 2013

(HealthDay)—For patients with type 2 diabetes, higher self-reported depression symptoms and antidepressant medicine (ADM) use in the previous year are independently associated with developing certain cardiovascular ...

Initiating statins linked to increased risk of T2DM

Jun 17, 2013

(HealthDay)—Initiating statin therapy is associated with an increased risk of type 2 diabetes, which is not explained by differential survival, according to a study published in the May issue of Diabetes Ca ...

Recommended for you

Blood glucose levels set for achieving HbA1c targets

Apr 11, 2014

(HealthDay)—The average self-monitored blood glucose (SMBG) concentrations needed at premeal, postmeal, and bedtime have been established to achieve a range of hemoglobin A1c (HbA1c) targets, according ...

Women with diabetes less likely to have a mammogram

Apr 11, 2014

Women with diabetes are 14 per cent less likely to be screened for breast cancer compared to women without diabetes, according to a study by researchers at the Institute for Clinical Evaluative Sciences (ICES) and Women's ...

Nonalcoholic fatty liver disease linked to CKD in T1DM

Apr 09, 2014

(HealthDay)—For patients with type 1 diabetes, nonalcoholic fatty liver disease (NAFLD) is independently associated with the risk of incident chronic kidney disease (CKD), according to a study published ...

Common diabetes treatment could extend hypoglycaemia

Apr 08, 2014

(Medical Xpress)—Researchers at the University of Adelaide have discovered that a common treatment for people with type 2 diabetes could cause longer-than-normal periods of the low blood sugar reaction hypoglycaemia, which ...

User comments