US liver-related deaths underestimated for decades

U.S. liver-related deaths underestimated for decades
Using an updated definition of liver-related causes of death raised the count of liver mortality in the National Death Registry in 2008 approximately two-fold, according to research published in the August issue of Gastroenterology.

(HealthDay)—Using an updated definition of liver-related causes of death raised the count of liver mortality in the National Death Registry in 2008 approximately two-fold, according to research published in the August issue of Gastroenterology.

Sumeet K. Asrani, M.D., of the Mayo Clinic College of Medicine in Rochester, Minn., and colleagues used a revised definition of liver-related causes of death to update from the Rochester Epidemiology Project from 1999 to 2008 and from the National Death Registry from 1979 to 2008.

The researchers found that using the National Center for Health Statistics definition would have captured only 71 deaths (27.2 percent) of the 261 liver-related deaths in the Rochester Epidemiology Project database. Among cases involving viral hepatitis or hepatobiliary cancer as the cause of death, immediate cause of death was liver-related in 96.9 and 94.3 percent of cases, respectively. For 2008 data from the National Death Registry, applying the updated definition raised the count of liver mortality from 11.7 to 25.7 deaths per 100,000.

"These data support that deaths due to and hepatobiliary cancers should be included in the enumeration of liver-related deaths to accurately represent the burden of ," the authors write.

More information: Abstract
Full Text

add to favorites email to friend print save as pdf

Related Stories

Recommended for you

S.Korea detects second foot-and-mouth case

20 minutes ago

South Korea on Monday reported its second case of foot-and-mouth disease in less than a week, triggering fearful memories of a devastating 2011 outbreak that forced the culling of millions of livestock.

Ebola kills Liberian doctor, 2 Americans infected

50 minutes ago

(AP)—One of Liberia's most high-profile doctors has died of Ebola, officials said Sunday, and an American physician was being treated for the deadly virus, highlighting the risks facing health workers trying ...

Hepatitis C virus genotype 1 is most prevalent worldwide

1 hour ago

In one of the largest prevalence studies to date, researchers from the U.K. provide national, regional, and global genotype prevalence estimates for the hepatitis C virus (HCV). Findings published in Hepatology, a journa ...

1 in 3000 blood donors in England infected with hepatitis E

1 hour ago

The first systematic analysis of hepatitis E virus (HEV) transmission by blood components indicates that about 1 in 3000 donors in England have HEV in their plasma. The findings, published in The Lancet, suggest that around ...

Biologic treatments for RA carry similar infection risk

1 hour ago

(HealthDay)—The risk of hospitalized bacterial infections in older rheumatoid arthritis (RA) patients is similar for rituximab or abatacept compared to etanercept, although it is higher for infliximab, ...

New oral drug regimens cure hardest-to-treat hepatitis C

1 hour ago

Two new pill-only antiviral drug regimens could provide shorter, more effective treatment options with fewer side effects for the majority of patients infected with hepatitis C, even those most difficult to treat, according ...

User comments