New moms and obese people risk complications from influenza

Although up to 500,000 people world-wide die of severe influenza each year, there has been no clear evidence about who is susceptible for influenza complications and it may not be who people think, says a study from McMaster University.

This is important because issues during past influenza seasons and pandemics have included vaccine shortage; the time needed to develop vaccines for specific and which groups are first in line for vaccination.

New mothers and obese people, two groups not typically regarded as risk groups, were found to have a higher risk of death and other severe outcomes from influenza, according to the global study sponsored by the World Health Organization.

But, in contrast to current assumption, ethnic minorities such as American Aboriginal People and pregnant women were not found to have more complicated influenza and would not need priority vaccination.

The report is published online in the BMJ, the journal of the British Medical Association.

"Policy makers and need to recognize the poor quality of evidence that has previously supported decisions on who receives vaccines during an epidemic," said Dr. Dominik Mertz, lead author of the study and an assistant professor of medicine of McMaster's Michael G. DeGroote School of Medicine.

"If we can define the risk groups we can optimally allocate vaccines, and that is particularly important when and if there is vaccine shortage, say during a new pandemic."

The researchers reviewed 239 observational studies between 1918 and 2011, looking at risk factors for complications of influenza including developing pneumonia or needing , admission to hospital or its or dying.

"These data reinforce the need to carefully define those conditions that lead to complications following infection with influenza," said Dr. Mark Loeb, senior author on the paper. He is also a microbiologist and professor of medicine of the Michael G. DeGroote School of Medicine.

More information: www.bmj.com/content/347/bmj.f5061

add to favorites email to friend print save as pdf

Related Stories

Flu vaccination protects patients at risk for acute MI

Aug 22, 2013

(HealthDay)—Recent influenza does not predict acute myocardial infarction (AMI), but vaccination offers a significant protective benefit for the prevention of AMI, according to research published online ...

Recommended for you

Recorded Ebola deaths top 7,000

8 hours ago

The worst Ebola outbreak on record has now killed more than 7,000 people, with many of the latest deaths reported in Sierra Leone, the World Health Organization said as United Nations Secretary-General Ban ...

Liberia holds Senate vote amid Ebola fears (Update)

12 hours ago

Health workers manned polling stations across Liberia on Saturday as voters cast their ballots in a twice-delayed Senate election that has been criticized for its potential to spread the deadly Ebola disease.

Evidence-based recs issued for systemic care in psoriasis

Dec 19, 2014

(HealthDay)—For appropriately selected patients with psoriasis, combining biologics with other systemic treatments, including phototherapy, oral medications, or other biologic, may result in greater efficacy ...

Bacteria in caramel apples kills at least four in US

Dec 19, 2014

A listeria outbreak believed to originate from commercially packaged caramel apples has killed at least four people in the United States and sickened 28 people since November, officials said Friday.

Steroid-based treatment may answer needs of pediatric EoE patients

Dec 19, 2014

A new formulation of oral budesonide suspension, a steroid-based treatment, is safe and effective in treating pediatric patients with eosinophilic esophagitis (EoE), according to a new study in Clinical Gastroenterology and Hepatology, the official clinical practice journal ...

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.