MRI-guided cryoablation viable for recurrent prostate cancer

August 9, 2013
MRI-guided cryoablation viable for recurrent prostate cancer
In men with recurrent prostate cancer following radiation therapy, magnetic resonance imaging-guided focal cryoablation is feasible and seems safe, according to a study published in the August issue of Radiology.

(HealthDay)—In men with recurrent prostate cancer following radiation therapy, magnetic resonance imaging (MRI)-guided focal cryoablation is feasible and seems safe, according to a study published in the August issue of Radiology.

Joyce G.R. Bomers, from Radboud University Nijmegen Medical Centre in the Netherlands, and colleagues studied 10 consecutive patients with histopathologically proved recurrent after , without evidence of distant metastases. While patients were under , a urethral warmer was inserted, followed by transperineal insertion of cryoneedles during real-time MRI and insertion of a rectal warmer. MRI guidance was used to continuously monitor ice ball growth. Two cycles of freezing and thawing were conducted. Follow-up included a urologist visit, prostate-specific antigen level measurement, and multiparametric MRI at three, six, and 12 months.

The researchers found that all patients were successfully treated, although in one patient, the urethral warmer could not be inserted and the procedure was cancelled, but was repeated successfully two months later. Urinary retention was observed in another patient. A local recurrence or remnant tumor was identified at six months in two patients and at 12 months in another patient. Successful retreatment with MRI-guided focal cryoablation occurred in these three patients.

"MR imaging-guided focal cryoablation of recurrent prostate cancer after radiation therapy is feasible and safe," the authors write. "Initial results are promising; however, longer follow-up is needed and more patients must be studied."

One author disclosed to the medical technology industry.

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Icy therapy spot treats cancer in the lung

April 14, 2013

Frozen balls of ice can safely kill cancerous tumors that have spread to the lungs, according to the first prospective multicenter trial of cryoablation. The results are being presented at the Society of Interventional Radiology's ...

PET/MR effective for imaging recurrent prostate cancer

June 11, 2013

When prostate cancer makes a comeback, it becomes increasingly important to have exceptional imaging available to find all possible regions where cancer has spread to other parts of the body, or metastasized, in order to ...

Recommended for you

Strange circular DNA may offer new way to detect cancers

July 30, 2015

Strange rings of DNA that exist outside chromosomes are distinct to the cell types that mistakenly produced them, researchers have discovered. The finding raises the tantalizing possibility that the rings could be used as ...

New treatment options for a fatal leukemia

July 27, 2015

In industrialized countries like in Europe, acute lymphoblastic leukemia is the most common form of cancer in children. An international research consortium lead by pediatric oncologists from the Universities of Zurich and ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.