Severe hypoglycemia in diabetes tied to cardiac disease

August 16, 2013
Severe hypoglycemia in diabetes tied to cardiac disease
For patients with type 1 and type 2 diabetes, severe hypoglycemia is associated with severe hypertension, hypokalemia, and QT prolongation, according to a study published online Aug. 12 in Diabetes Care.

(HealthDay)—For patients with type 1 and type 2 diabetes, severe hypoglycemia is associated with severe hypertension, hypokalemia, and QT prolongation, according to a study published online Aug. 12 in Diabetes Care.

Tetsuro Tsujimoto, M.D., from the National Center for Global Health and Medicine in Tokyo, and colleagues conducted a to assess vital signs, QT intervals, and newly diagnosed cardiovascular disease during severe hypoglycemia in patients with type 1 and type 2 diabetes. A total of 414 cases of severe hypoglycemia that could not be resolved by the patients themselves in a pre-hospital setting were included in analyses.

The researchers observed no significant difference in the median blood glucose levels between patients with type 1 (88 patients) and type 2 (326 patients) diabetes. In the group, the incidences of severe hypertension, hypokalemia, and QT prolongation were 19.8, 42.4, and 50.0 percent, respectively. For patients with type 2 diabetes, the corresponding proportions were 38.8, 36.3, and 59.9 percent, with a significant difference for the incidence of severe hypertension between the groups. Only in the type 2 diabetes group were newly-diagnosed cardiovascular disease during severe hypoglycemia (1.5 percent) and death (1.8 percent) observed. There was a significant difference in the group for between the deceased and surviving patients.

"Type 1 and type 2 diabetic patients with severe hypoglycemia experienced many critical problems that could lead to cardiovascular disease, fatal arrhythmia, and death," the authors write.

Explore further: Risk of comorbidities up with hypoglycemia in T2DM

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Risk of comorbidities up with hypoglycemia in T2DM

April 8, 2013

(HealthDay)—For patients with type 2 diabetes, hypoglycemia, regardless of its severity, correlates with a significantly increased risk of cardiovascular events, all-cause hospitalization, and mortality, according to research ...

Hospital hypoglycemia rates up in black men with diabetes

May 14, 2013

(HealthDay)—Home diabetes regimens partially explain the increased risk of having a hypoglycemia event during hospitalization among older African-American men with diabetes, according to a study published in the April issue ...

ADA: insulin-pump tx with threshold-suspend beneficial

June 24, 2013

(HealthDay)—For patients with type 1 diabetes and documented nocturnal hypoglycemia, insulin-pump therapy with a threshold-suspend feature reduces nocturnal hypoglycemia over a three-month period, according to a study published ...

Recommended for you

Low-carb diet may aid your metabolism

December 2, 2016

(HealthDay)—Eating low-carbohydrate meals may lead to healthy changes in a woman's metabolism that don't occur when consuming higher-carbohydrate meals, a small study suggests.

Research shows nerve growth protein controls blood sugar

November 14, 2016

Research led by a Johns Hopkins University biologist demonstrates the workings of a biochemical pathway that helps control glucose in the bloodstream, a development that could potentially lead to treatments for diabetes.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.