Study examines Parkinsonism in one county in Minnesota

Walter A. Rocca, M.D., M.P.H., of the Mayo Clinic, Rochester, Minn., and colleagues examined the incidence of dementia with Lewy bodies (DLB) and Parkinson disease dementia (PDD) in a JAMA Neurology study of residents in Olmsted County, Minn., over a 15-year period.

Limited information is available about the incidence of DLB or PDD in the general population so researchers used a well-defined population to help better characterize the two disorders, according to the study background.

Among 542 cases of parkinsonism, 64 patients had DLB and 46 had PDD. The overall incidence rate of DLB was 3.5 cases per 100,000 person-years, the incidence rate of PDD was 2.5 and both increased with age, according to the results. Patients with DLB were younger at the onset of symptoms than patients with PDD and had more and cognitive fluctuations.

"In conclusion, our study provides unique population-based data on the incidence of DLB and PDD in Olmsted County. Similar to Parkinson disease, the risk of DLB increases with older age and is more frequent in men," the study concludes.

More information: JAMA Neurol. Published online September 16, 2013. DOI: 10.1001/.jamaneurol.2013.3579

add to favorites email to friend print save as pdf

Related Stories

Five CSF markers differentiate dementia, parkinsonism

Aug 28, 2012

(HealthDay)—Levels of five different cerebrospinal fluid (CSF) biomarkers are able to improve differentiation between common dementia and parkinsonian disorders, according to a study published online Aug. ...

Donepezil found helpful in dementia with lewy bodies

Jul 31, 2012

(HealthDay) -- For patients with dementia with Lewy bodies (DLB), treatment with 5 or 10 mg/day donepezil is associated with significant cognitive, behavioral, and global function improvements, according to ...

Recommended for you

Weight and eating habits in Parkinson's disease

Nov 20, 2014

Patients affected by Parkinson's disease often show marked changes in body weight: they may gain or lose a lot of weight depending on the stage of the disease, or they may put on up to ten kilos after deep brain stimulation ...

Scientists create Parkinson's disease in a dish

Nov 06, 2014

A team of scientists led by The New York Stem Cell Foundation (NYSCF) Research Institute successfully created a human stem cell disease model of Parkinson's disease in a dish. Studying a pair of identical ...

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.