Study examines Parkinsonism in one county in Minnesota

Walter A. Rocca, M.D., M.P.H., of the Mayo Clinic, Rochester, Minn., and colleagues examined the incidence of dementia with Lewy bodies (DLB) and Parkinson disease dementia (PDD) in a JAMA Neurology study of residents in Olmsted County, Minn., over a 15-year period.

Limited information is available about the incidence of DLB or PDD in the general population so researchers used a well-defined population to help better characterize the two disorders, according to the study background.

Among 542 cases of parkinsonism, 64 patients had DLB and 46 had PDD. The overall incidence rate of DLB was 3.5 cases per 100,000 person-years, the incidence rate of PDD was 2.5 and both increased with age, according to the results. Patients with DLB were younger at the onset of symptoms than patients with PDD and had more and cognitive fluctuations.

"In conclusion, our study provides unique population-based data on the incidence of DLB and PDD in Olmsted County. Similar to Parkinson disease, the risk of DLB increases with older age and is more frequent in men," the study concludes.

More information: JAMA Neurol. Published online September 16, 2013. DOI: 10.1001/.jamaneurol.2013.3579

Related Stories

Five CSF markers differentiate dementia, parkinsonism

date Aug 28, 2012

(HealthDay)—Levels of five different cerebrospinal fluid (CSF) biomarkers are able to improve differentiation between common dementia and parkinsonian disorders, according to a study published online Aug. ...

Donepezil found helpful in dementia with lewy bodies

date Jul 31, 2012

(HealthDay) -- For patients with dementia with Lewy bodies (DLB), treatment with 5 or 10 mg/day donepezil is associated with significant cognitive, behavioral, and global function improvements, according to ...

Recommended for you

Apple highlights Parkinson's app

date Mar 10, 2015

A new iPhone mobile app which allows patients with Parkinson's disease to track their symptoms in real time and share this information with researchers was featured by Apple executives today during the company's ...

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.