Model can predict preemie neonatal outcome severity

Model can predict preemie neonatal outcome severity

(HealthDay)—A statistical prediction model comprising eight characteristics can be used to determine the severity of neonatal outcomes for infants born at 23 to 30 weeks of gestation, according to a study published online Sept. 23 in Pediatrics.

Wen J. Ge, from Mount Sinai Hospital in Toronto, and colleagues developed and validated a model to predict the severity of in infants born at 23 to 30 weeks of gestation. A national cohort of infants admitted to level III units (NICUs) in Canada in 2010 to 2011 were identified from the Canadian Neonatal Network database.

The researchers found that 37 percent of the 6,106 eligible infants survived without morbidity; 32 percent survived with mild morbidity; and 21 percent survived with severe morbidity. Ten percent of infants died. The model predictors included gestational age, small for gestational age (less than 10th percentile), gender, Score for Neonatal Acute Physiology version II >20, outborn status, antenatal corticosteroid use, receipt of surfactant, and on the first day of admission. Internal bootstrap validation confirmed high model discrimination. The probabilities predicted were consistent with the outcomes observed.

"Neonatal outcomes ranging from mortality to survival without morbidity in extremely preterm infants can be predicted on their first day in the NICU by using a multinomial model with good discrimination and calibration," the authors write.

More information: Abstract
Full Text (subscription or payment may be required)

add to favorites email to friend print save as pdf

Related Stories

Recommended for you

Neonatal vitamin K refusal tied to nonimmunization

19 hours ago

(HealthDay)—While neonatal vitamin K refusal is rare, parents who refuse vitamin K are less likely to immunize their child, according to a study published online Aug. 18 in Pediatrics.

Teen sleeplessness piles on risk for obesity

21 hours ago

Teenagers who don't get enough sleep may wake up to worse consequences than nodding off during chemistry class. According to new research, risk of being obese by age 21 was 20 percent higher among 16-year-olds who got less ...

Researchers show economic disparities impact infant health

22 hours ago

Women who are poor experience higher cortisol levels in pregnancy and give birth to infants with elevated levels of the stress hormone, putting them at greater risk for serious disease later in life, according to a new research ...

User comments