Model can predict preemie neonatal outcome severity

September 24, 2013
Model can predict preemie neonatal outcome severity

(HealthDay)—A statistical prediction model comprising eight characteristics can be used to determine the severity of neonatal outcomes for infants born at 23 to 30 weeks of gestation, according to a study published online Sept. 23 in Pediatrics.

Wen J. Ge, from Mount Sinai Hospital in Toronto, and colleagues developed and validated a model to predict the severity of in infants born at 23 to 30 weeks of gestation. A national cohort of infants admitted to level III units (NICUs) in Canada in 2010 to 2011 were identified from the Canadian Neonatal Network database.

The researchers found that 37 percent of the 6,106 eligible infants survived without morbidity; 32 percent survived with mild morbidity; and 21 percent survived with severe morbidity. Ten percent of infants died. The model predictors included gestational age, small for gestational age (less than 10th percentile), gender, Score for Neonatal Acute Physiology version II >20, outborn status, antenatal corticosteroid use, receipt of surfactant, and on the first day of admission. Internal bootstrap validation confirmed high model discrimination. The probabilities predicted were consistent with the outcomes observed.

"Neonatal outcomes ranging from mortality to survival without morbidity in extremely preterm infants can be predicted on their first day in the NICU by using a multinomial model with good discrimination and calibration," the authors write.

Explore further: Surviving premature babies in Malawi continue to have poor growth rates and development delay

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Elective induction at term tied to lower odds of cesarean

September 13, 2013

(HealthDay)—Compared with expectant management, elective induction at term (37 to 40 weeks of gestation) is associated with reduced likelihood of cesarean delivery, according to a study published online Sept. 6 in Obstetrics ...

Recommended for you

Youth dance classes score low in physical activity

May 18, 2015

For parents who send their kids to dance classes to get some exercise, a new study from researchers at University of California, San Diego School of Medicine suggests most youth dance classes provide only limited amounts ...

Roller coaster rides trigger pediatric stroke

December 11, 2014

Riding a couple roller coasters at an amusement park appears to have triggered an unusual stroke in a 4-year-old boy, according to a report in the journal Pediatric Neurology.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.