Protein illustrates muscle damage

November 11, 2013

Researchers at McMaster University have discovered a protein that is only detectable after muscle damage, and it may serve as a way to measure injury.

"Our results highlight the protein called Xin as a muscle damage biomarker," said Thomas Hawke, principal investigator and an associate professor for the Department of Pathology and Molecular Medicine at McMaster.

"Regardless of the way in which muscle was damaged, either through trauma or disease, Xin was strongly correlated to the degree of damage."

The research will be published in the December issue of The American Journal of Pathology.

The paper explains that the protein Xin is undetectable in of healthy subjects. However, when muscle damage occurs, Xin becomes detectable and shows a pattern that highly correlates with the amount of .

The researchers found this to be true for healthy subjects who have damaged their muscles with intense exercise as well as numerous patients with various forms of , including muscular dystrophy.

Explore further: Another muscular dystrophy mystery solved; MU scientists inch closer to a therapy for patients

Related Stories

Recommended for you

New findings offer hope for diabetic wound healing

November 23, 2015

University of Notre Dame researchers have discovered a compound that accelerates diabetic wound healing, which may open the door to new treatment strategies. Non-healing chronic wounds are a major complication of diabetes, ...

'Healthy' foods differ by individual

November 19, 2015

Ever wonder why that diet didn't work? An Israeli study tracking the blood sugar levels of 800 people over a week suggests that even if we all ate the same meal, how it's metabolized would differ from one person to another. ...


Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.