Protein illustrates muscle damage

Researchers at McMaster University have discovered a protein that is only detectable after muscle damage, and it may serve as a way to measure injury.

"Our results highlight the protein called Xin as a muscle damage biomarker," said Thomas Hawke, principal investigator and an associate professor for the Department of Pathology and Molecular Medicine at McMaster.

"Regardless of the way in which muscle was damaged, either through trauma or disease, Xin was strongly correlated to the degree of damage."

The research will be published in the December issue of The American Journal of Pathology.

The paper explains that the protein Xin is undetectable in of healthy subjects. However, when muscle damage occurs, Xin becomes detectable and shows a pattern that highly correlates with the amount of .

The researchers found this to be true for healthy subjects who have damaged their muscles with intense exercise as well as numerous patients with various forms of , including muscular dystrophy.

add to favorites email to friend print save as pdf

Related Stories

Recommended for you

Team untangles the biological effects of blue light

7 hours ago

Blue light can both set the mood and set in motion important biological responses. Researchers at the University of Pennsylvania's School of Medicine and School of Arts and Sciences have teased apart the ...

Mouse model provides new insight in to preeclampsia

8 hours ago

Worldwide, preeclampsia is a leading cause of maternal deaths and preterm births. This serious pregnancy complication results in extremely high blood pressure and organ damage. The onset of preeclampsia is associated with ...

Scientists unravel the mystery of a rare sweating disorder

8 hours ago

An international research team discovered that mutation of a single gene blocks sweat production, a dangerous condition due to an increased risk of hyperthermia, also known as heatstroke. The gene, ITPR2, controls a basic ...

User comments