Spatiotemporal analysis emphasizes value of vaccination

November 28, 2013
Spatiotemporal analysis emphasizes value of vaccination
Spatiotemporal data emphasizes the importance of vaccination programs, according to research published in the Nov. 28 issue of the New England Journal of Medicine.

(HealthDay)—Spatiotemporal data emphasizes the importance of vaccination programs, according to research published in the Nov. 28 issue of the New England Journal of Medicine.

Willem G. van Panhuis, M.D., Ph.D., from the University of Pittsburgh, and colleagues digitized all weekly surveillance reports of nationally notifiable diseases for U.S. cities and states published from 1888 to 2011 using data from the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report and its precursor journals. A detailed analysis was conducted, focusing on eight vaccine-preventable contagious diseases.

Assuming that the difference in before and after vaccine licensure was attributable solely to vaccination programs, the researchers estimate that vaccines prevented 103.1 million cases of contagious diseases since 1924. The number of cases prevented per disease varied with prevaccination incidence and the vaccine program duration, with the most cases prevented for diphtheria (about 40 million) followed by measles (about 35 million cases). In the years after vaccination, the proportion of cases of each disease prevented increased with varying rates. During the first five years after the licensure, 22.2 percent more cases were prevented each year. By year five after licensure, 95 percent of measles cases had been prevented, compared with year eight for polio, 19 years for diphtheria, and 17 years for pertussis. Since the 1980s, multiple resurgences of , rubella, mumps, and pertussis have occurred.

"Our analysis shows how high-resolution spatiotemporal data can be effectively used to illustrate these trends at the national and local levels and to inform public opinion about the necessity of vaccination programs," the authors write.

Explore further: Study unlocks trove of public health data to help fight deadly contagious diseases

More information: Full Text (subscription or payment may be required)

Related Stories

Timing of first dose of measles vaccine questioned

October 21, 2013

(HealthDay)—Children who receive the first dose of a two-dose schedule of measles vaccine at 12 to 13 months compared with 15 months or later have a greater risk of developing measles, according to a study published online ...

Recommended for you

Zika virus infection alters human and viral RNA

October 20, 2016

Researchers at University of California San Diego School of Medicine have discovered that Zika virus infection leads to modifications of both viral and human genetic material. These modifications—chemical tags known as ...

Food-poisoning bacteria may be behind Crohn's disease

October 19, 2016

People who retain a particular bacterium in their gut after a bout of food poisoning may be at an increased risk of developing Crohn's disease later in life, according to a new study led by researchers at McMaster University.

Neurodevelopmental model of Zika may provide rapid answers

October 19, 2016

A newly published study from researchers working in collaboration with the Regenerative Bioscience Center at the University of Georgia demonstrates fetal death and brain damage in early chick embryos similar to microcephaly—a ...

Scientists uncover new facets of Zika-related birth defects

October 17, 2016

In a study that could one day help eliminate the tragic birth defects caused by Zika virus, scientists from the Florida campus of The Scripps Research Institute (TSRI) have elucidated how the virus attacks the brains of newborns, ...


Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.