Spatiotemporal analysis emphasizes value of vaccination

November 28, 2013
Spatiotemporal analysis emphasizes value of vaccination
Spatiotemporal data emphasizes the importance of vaccination programs, according to research published in the Nov. 28 issue of the New England Journal of Medicine.

(HealthDay)—Spatiotemporal data emphasizes the importance of vaccination programs, according to research published in the Nov. 28 issue of the New England Journal of Medicine.

Willem G. van Panhuis, M.D., Ph.D., from the University of Pittsburgh, and colleagues digitized all weekly surveillance reports of nationally notifiable diseases for U.S. cities and states published from 1888 to 2011 using data from the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report and its precursor journals. A detailed analysis was conducted, focusing on eight vaccine-preventable contagious diseases.

Assuming that the difference in before and after vaccine licensure was attributable solely to vaccination programs, the researchers estimate that vaccines prevented 103.1 million cases of contagious diseases since 1924. The number of cases prevented per disease varied with prevaccination incidence and the vaccine program duration, with the most cases prevented for diphtheria (about 40 million) followed by measles (about 35 million cases). In the years after vaccination, the proportion of cases of each disease prevented increased with varying rates. During the first five years after the licensure, 22.2 percent more cases were prevented each year. By year five after licensure, 95 percent of measles cases had been prevented, compared with year eight for polio, 19 years for diphtheria, and 17 years for pertussis. Since the 1980s, multiple resurgences of , rubella, mumps, and pertussis have occurred.

"Our analysis shows how high-resolution spatiotemporal data can be effectively used to illustrate these trends at the national and local levels and to inform public opinion about the necessity of vaccination programs," the authors write.

More information: Full Text (subscription or payment may be required)

Related Stories

Timing of first dose of measles vaccine questioned

October 21, 2013

(HealthDay)—Children who receive the first dose of a two-dose schedule of measles vaccine at 12 to 13 months compared with 15 months or later have a greater risk of developing measles, according to a study published online ...

Recommended for you

Experimental MERS vaccine shows promise in animal studies

July 28, 2015

A two-step regimen of experimental vaccines against Middle East respiratory syndrome (MERS) prompted immune responses in mice and rhesus macaques, report National Institutes of Health scientists who designed the vaccines. ...

Can social isolation fuel epidemics?

July 21, 2015

Conventional wisdom has it that the more people stay within their own social groups and avoid others, the less likely it is small disease outbreaks turn into full-blown epidemics. But the conventional wisdom is wrong, according ...

Lack of knowledge on animal disease leaves humans at risk

July 20, 2015

Researchers from the University of Sydney have painted the most detailed picture to date of major infectious diseases shared between wildlife and livestock, and found a huge gap in knowledge about diseases which could spread ...

IBD genetically similar in Europeans and non-Europeans

July 20, 2015

The first genetic study of inflammatory bowel disease (IBD) to include individuals from diverse populations has shown that the regions of the genome underlying the disease are consistent around the world. This study, conducted ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.