New targeted therapy to treat facial lesions

November 8, 2013

Research conducted by Roy G. Geronemus, M.D. and Yoon-Soo Cindy Bae-Harboe, M.D., was selected as Editor's Choice for the November 2013 issue of Lasers in Surgery and Medicine (LSM).

The manuscript titled "Targeted Topical and Combination Laser Surgery for the Treatment of Angiofibromas" was published in LSM, the official journal of the American Society for Laser Medicine and Surgery, Inc. (ASLMS).

Using a variety of laser technologies and a new topical medicine, the authors described an innovative way to treat angiofibromas, characteristically seen in patients with Tuberous Sclerosis. Angiofibromas are persistent facial lesions that are difficult to treat as they recur. The application of a new , topical sirolimus, works synergistically with and prolongs the effects of treatment.

"We described our method of combining these treatments to manage the angiofibromas of Tuberous Sclerosis. We hope to continue to pioneer innovative approaches to treating difficult skin problems by incorporating novel medical therapies with laser technology," said Dr. Geronemus.

Dr. Geronemus directs the Laser & Skin Surgery Center of New York, where they are investigating a diverse array of skin concerns including, but not limited to: scars, stretch marks, volume loss, alternatives to neuromodulators for rhytides, fat reduction, tattoo removal, port wine stains, dyspigmentation, alopecia, hair removal, and more. He is Clinical Professor of Dermatology at the New York University Medical Center.

The Editor-in-Chief of LSM, J. Stuart Nelson, M.D., Ph.D. commented on the study, "The angiofibromas of Tuberous Sclerosis (TS) is a frustrating, persistent, recurrent skin problem with very limited treatment options. In the manuscript, the authors explore the potential benefits of merging novel topical agents with laser surgery to increase penetration of targeted therapy into the site of pathology. This report compels investigators to study this procedure in larger randomized clinical trials so that patients suffering from the stigma of these lesions can be effectively treated."

Explore further: Pulsed dye laser effective on port-wine stains in infants

More information: www.aslms.org/professional/documents/EditorsChoiceLSMNov459.pdf

Related Stories

Pulsed dye laser effective on port-wine stains in infants

February 28, 2012

(HealthDay) -- Pulsed dye laser (PDL) treatment at two-, three-, and four-week intervals is effective for infants with facial port-wine stains (PWS), with minimal short-term side effects, according to a study published online ...

Novel approach found for treating hypertrophic scars

March 27, 2013

(HealthDay)—Same-session therapy with fractional ablative laser treatment followed immediately with topical application of triamcinolone acetonide suspension is effective in treating patients with hypertrophic and restrictive ...

Ablative carbon dioxide laser effective for rhinophyma

October 17, 2013

(HealthDay)—Good cosmetic outcomes are possible using fractionated ablative carbon dioxide laser therapy for mild-to-moderate cases of rhinophyma, according to research published online Oct. 5 in Lasers in Surgery and Medicine.

Treatment interval doesn't affect benefit of acne laser Tx

October 19, 2013

(HealthDay)—Fractional CO2 laser treatment is safe and seems effective for atrophic acne scars, with no difference observed for treatment with a one- or three-month interval, according to a study published online Sept. ...

Recommended for you

A recipe for long-lasting livers

April 22, 2015

People waiting for organ transplants may soon have higher hopes of getting the help that they need in time. Researchers at the RIKEN Center for Developmental Biology have developed a new technique that extends the time that ...

Surgeon to offer ideas on a way to do human head transplants

February 26, 2015

Sergio Canavero of the Turin Advanced Neuromodulation Group has made it known that he intends to announce at this summer's American Academy of Neurological and Orthopedic Surgeons meeting, that he believes he has put together ...

New tool helps guide brain cancer surgery

July 3, 2014

A tool to help brain surgeons test and more precisely remove cancerous tissue was successfully used during surgery, according to a Purdue University and Brigham and Women's Hospital study.

New imaging technique sharpens surgeons' vision

February 11, 2014

Which superhuman power would you choose for help on the job? For Dr. Julie Margenthaler, it's a technology that brings to mind X-ray vision, used for the first time Monday during an operation to remove a patient's lymph node.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.