Earlier adiposity rebound linked to metabolic syndrome

Earlier adiposity rebound linked to metabolic syndrome

(HealthDay)—The age of adiposity rebound (AR), at which time body mass index (BMI) starts to rise after infancy, is associated with future development of metabolic syndrome, according to a study published online Dec. 23 in Pediatrics.

Satomi Koyama, M.D., Ph.D., from the Dokkyo Medical University in Tochigi, Japan, and colleagues examined whether the age of AR is related to future occurrence of . Serial measurements of BMI were collected for 271 children born in 1995 and 1996 at the ages of 4, 8, 12, 18, and 24 months and every year thereafter through age 12. The age of AR was calculated based on BMI measures; plasma lipids and blood pressure were assessed at age 12.

The researchers observed a correlation between earlier AR (before age 4) with higher BMI (≥20 kg/m²) and a lipoprotein phenotype indicating insulin resistance. This phenotype included elevated triglycerides, apolipoprotein B, and atherogenic index. In addition, the phenotype included decreased high-density lipoprotein cholesterol in boys and elevated apolipoprotein B in girls at 12. In boys, earlier AR correlated with increased .

"Detection of early AR may permit identification of young children at risk for developing later metabolic syndrome and provide an opportunity for preventive intervention," the authors write.

Several authors disclosed financial ties to the medical device and medical technology industries.

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

FTO linked to BMI, BMI-for-age Z score in children

date Nov 04, 2013

(HealthDay)—For children from the Brazilian Amazon, FTO rs9939609 allele is associated with increased body mass index (BMI) and BMI-for-age Z scores, with the effect significantly modified by vitamin D stat ...

Cataract risk up for statin users with type 2 diabetes

date Aug 13, 2012

(HealthDay) -- Statin use, which is substantially higher in patients with type 2 diabetes, correlates with an increased risk of age-related (AR) cataracts, according to a study published in the August issue ...

Recommended for you

Obese teens in study less likely to use contraception

date Jul 01, 2015

A study of nearly 1,000 teens found that sexually active obese adolescents were significantly less likely to use contraception than normal weight peers, putting them at higher risk of unintended pregnancy.

Extracurricular sports produce disciplined preteens

date Jul 01, 2015

Regular, structured extracurricular sports seem to help kids develop the discipline they need in order to engage effectively in the classroom, according to a new study led by Linda Pagani of the University ...

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.