Data unclear for heart failure outcomes in US versus Canada

Data unclear for heart failure outcomes in U.S. versus canada
Evidence for the difference in outcomes for heart failure patients in Canada versus the United States differs depending on the source of the data, according to research published in the December issue of the Journal of the American College of Cardiology: Heart Failure.

(HealthDay)—Evidence for the difference in outcomes for heart failure patients in Canada versus the United States differs depending on the source of the data, according to research published in the December issue of the Journal of the American College of Cardiology: Heart Failure.

Padma Kaul, Ph.D., of the University of Alberta in Edmonton, Canada, and colleagues examined data from the Acute Study of Clinical Effectiveness of Nesiritide in Decompensated Heart Failure (ASCEND-HF) trial and population-based cohorts to assess the inter-country differences in outcomes of patients with heart failure.

The researchers found that Canadian patients enrolled in the randomized trial were older, more likely to be white, and had lower body weights and lower blood pressures than U.S. patients. Trial results showed that Canadian patients had significantly lower baseline-adjusted odds of 30-day mortality (odds ratio, 0.46) and better health-related quality of life than U.S. patients. In contrast, population-based data showed that U.S. patients had significantly lower unadjusted in-hospital mortality than Canadian patients (3.4 versus 11.1 percent).

"Evidence on inter-country differences in outcomes of patients hospitalized with in Canada and the United States remains equivocal," the authors write.

Scios Inc. funded the ASCEND-HF study.

More information: Full Text (subscription or payment may be required)

add to favorites email to friend print save as pdf

Related Stories

Fragility impacts quality of life in heart failure

Dec 03, 2013

(HealthDay)—For patients with heart failure, fragility is associated with the perception of quality of life, according to a study published in the Dec. 1 issue of The American Journal of Cardiology.

Recommended for you

New drowning rescue steps could save lives

18 hours ago

A New Zealand researcher from the University of Auckland, Jonathon Webber, is part of an international study team that has come up with a new way to help prevent drowning.

User comments