Study identifies risk factors for non-fatal overdoses

January 8, 2014

Researchers from Boston University School of Medicine (BUSM) and Boston Medical Center (BMC) have identified that injection frequency and taking anti-retroviral therapy for HIV are risk factors for nonfatal drug overdoses among Russians who are HIV positive and inject drugs. Alexander Walley, MD, MSc, an attending physician in general internal medicine at BMC and an assistant professor of medicine at BUSM, is the study's lead author.

Published in the journal AIDS Care, the study was done in collaboration with the Pavlov State Medical University in Russia.

"Non-fatal overdose among HIV-infected Russians who inject drugs is common, however our study is the first to identify associated with those cases," said Walley.

The researchers analyzed baseline data of 294 with 30-day injection drug use who were taking part in an HIV secondary prevention trial for individuals who self-reported "heavy" alcohol use and in the past six months.

More than three quarters of the participants, 76 percent, reported a lifetime history of a non-fatal overdose while 16 percent reported a non-fatal overdose in the previous three months. The data showed that the previous month's injection history and anti-retroviral therapy at the time the participants were interviewed were associated with a non-fatal overdose within the previous three months.

"Our study data demonstrates that these individuals could benefit from overdose prevention efforts," added Walley.

Related Stories

Study analyzes link between HIV infection and overdose risk

December 12, 2011

A study from Rhode Island Hospital is the first to systematically review and analyze the literature on the association between HIV infection and overdose risk. The findings show a 74 percent greater risk of overdose among ...

Recommended for you

HVTN 505 vaccine induced antibodies nonspecific for HIV

July 30, 2015

A study by researchers at the National Institute of Allergy and Infectious Diseases and Duke University helps explain why the candidate vaccine used in the HVTN 505 clinical trial was not protective against HIV infection ...

Vitamin D status related to immune response to HIV-1

June 15, 2015

Vitamin D plays an important part in the human immune response and deficiency can leave individuals less able to fight infections like HIV-1. Now an international team of researchers has found that high-dose vitamin D supplementation ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.