Study identifies risk factors for non-fatal overdoses

Researchers from Boston University School of Medicine (BUSM) and Boston Medical Center (BMC) have identified that injection frequency and taking anti-retroviral therapy for HIV are risk factors for nonfatal drug overdoses among Russians who are HIV positive and inject drugs. Alexander Walley, MD, MSc, an attending physician in general internal medicine at BMC and an assistant professor of medicine at BUSM, is the study's lead author.

Published in the journal AIDS Care, the study was done in collaboration with the Pavlov State Medical University in Russia.

"Non-fatal overdose among HIV-infected Russians who inject drugs is common, however our study is the first to identify associated with those cases," said Walley.

The researchers analyzed baseline data of 294 with 30-day injection drug use who were taking part in an HIV secondary prevention trial for individuals who self-reported "heavy" alcohol use and in the past six months.

More than three quarters of the participants, 76 percent, reported a lifetime history of a non-fatal overdose while 16 percent reported a non-fatal overdose in the previous three months. The data showed that the previous month's injection history and anti-retroviral therapy at the time the participants were interviewed were associated with a non-fatal overdose within the previous three months.

"Our study data demonstrates that these individuals could benefit from overdose prevention efforts," added Walley.

add to favorites email to friend print save as pdf

Related Stories

Study analyzes link between HIV infection and overdose risk

Dec 12, 2011

A study from Rhode Island Hospital is the first to systematically review and analyze the literature on the association between HIV infection and overdose risk. The findings show a 74 percent greater risk of overdose among ...

Researchers: Program discourages HIV transmission in Russia

Jul 11, 2008

(Boston)-Researchers from Boston University School of Medicine (BUSM) and Boston Medical Center (BMC) found that sexual behavior counseling during drug addiction treatment should be considered an important component among ...

Recommended for you

Model explains why HIV prevention dosing differs by sex

Oct 30, 2014

A mathematical model developed by NIH grantees predicts that women must take the antiretroviral medication Truvada daily to prevent HIV infection via vaginal sex, whereas just two doses per week can protect men from HIV infection ...

Tourism as a driver of illicit drug use, HIV risk in the DR

Oct 29, 2014

The Caribbean has the second highest global human immunodeficiency virus (HIV) prevalence in the world outside of Sub-Saharan Africa, with HIV/AIDS as leading cause of death among people aged 20–59 years within the region. ...

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.