Kidney injury not uncommon after cardiovascular intervention

Kidney injury not uncommon after cardiovascular intervention

(HealthDay)—Acute kidney injury (AKI) is seen in about 7 percent of patients undergoing percutaneous coronary intervention (PCI) and is associated with significant in-hospital mortality, according to research published in the Jan. 1 issue of the Journal of the American College of Cardiology: Cardiovascular Interventions.

Thomas T. Tsai, M.D., of the University of Colorado in Denver, and colleagues analyzed data from a national registry for 985,737 consecutive patients who underwent PCIs. The authors sought to identify patient characteristics associated with AKI.

The researchers found that AKI occurred in 7.1 percent of patients undergoing PCI, and new was required in 0.3 percent. Factors that were strongly associated with the development of AKI were ST-segment elevation (STEMI) presentation (odds ratio [OR], 2.60), severe chronic kidney disease (OR, 3.59), and cardiogenic shock (OR, 2.92). The in-hospital mortality rate was significantly higher in patients with AKI (9.7 percent) and those requiring dialysis (34 percent) than in those without AKI (0.5 percent). After adjustment for multiple variables, AKI (OR, 7.8) and dialysis (OR, 21.7) remained independently associated with in-hospital mortality.

"Defining strategies to minimize the risk of AKI in patients undergoing PCI are needed to improve the safety and outcomes of the procedure," the authors write.

Several authors disclosed financial ties to pharmaceutical and medical device companies.

More information: Full Text (subscription or payment may be required)

add to favorites email to friend print save as pdf

Related Stories

Acute kidney injury increased for some over last decade

Nov 01, 2013

(HealthDay)—Over the last decade there has been an increase in the incidence of acute kidney injury (AKI), but a decrease in the incidence of AKI requiring dialysis, among elderly patients hospitalized ...

Acute kidney injury may be more deadly than heart attacks

Dec 05, 2013

Acute kidney injury, a condition that is common but often asymptomatic, may be more deadly than a heart attack, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN ...

Recommended for you

Results of RIBS IV trial reported

7 hours ago

A new clinical trial comparing the use of everolimus-eluting stents (EES) and drug-eluting balloons (DEB) in treating in-stent restenosis (ISR) from drug-eluting stents found that EES provided superior late angiographic results ...

Results of DKCRUSH-VI trial reported

7 hours ago

A new study found that fractional flow reserve (FFR)-guided provisional side branch (SB) stenting of true coronary bifurcation lesions yields similar outcomes to the current standard of care. The DKCRUSH-VI clinical trial ...

Results of IVUS-CTO trial reported at TCT 2014

7 hours ago

A new study found that intravascular ultrasound (IVUS) -guided intervention in patients with chronic total occlusion (CTO) could improve outcomes compared to a conventional angiography-guided approach during percutaneous ...

Results of OCT STEMI trial reported at TCT 2014

7 hours ago

The first randomized trial to examine serial optical coherence tomography (OCT) in primary percutaneous coronary intervention (PCI) was reported at the 26th annual Transcatheter Cardiovascular Therapeutics (TCT) scientific ...

INR variability predicts warfarin adverse effects

13 hours ago

(HealthDay)—Unstable anticoagulation predicts warfarin adverse effects regardless of time in therapeutic range, according to a study published online Sept. 2 in Circulation: Cardiovascular Quality and Ou ...

User comments