Clinical trial shows stem cell injections reduce low pack pain (w/ Video)

by Melva Robertson
Clinical trial shows stem cell injections reduce low pack pain

A single injection of stem cells into degenerative discs reduced low back pain for at least 12 months according to results of a 100-patient, phase II, international clinical trial that included researchers at the Emory Orthopaedics & Spine Center.

W. Jeremy Beckworth, MD, assistant professor of Orthopaedics and Rehab Medicine, was part of the trial that used injections of bone marrow stem cells called mesenchymal precursor cells (MPCs) to reduce pain. On average researchers found a pain reduction greater than 50 percent at 12 months. Additionally, there was less need for , improvement in function, and less need for further surgical and non-surgical spine interventions. These results were found in patients with moderate to severe discogenic low back pain.

"These are very exciting findings," explains Beckworth. "The results provide significant hope for a condition that has been very tough to treat. Discogenic low back pain, a painful , is the most common cause of chronic low back ."

The phase II clinical trial builds on a previously reported preclinical study showing highly purified MPCs were able to repair and restore disc structure. All findings from the trial were statistically better for those receiving versus those in control groups.

This video is not supported by your browser at this time.

"Currently there is no adequate treatment for discogenic ," says Beckworth. "Both conservative and surgical treatments fall short. These positive results pave the way for a phase III study that may be starting later this year."

add to favorites email to friend print save as pdf

Related Stories

Recommended for you

Routines most vital in avoiding Ebola infection: WHO

4 hours ago

Meticulously following stringent routines when putting on and removing protective equipment is more important than the kind of gear health care workers use to ward off Ebola infection, the World Health Organization said Friday.

A look at latest Ebola developments

5 hours ago

No African countries are on the United Nations list of contributors to fight Ebola. With few exceptions, African governments and institutions are offering only marginal support as the continent faces its ...

Liberia opens one of largest Ebola treatment centers

6 hours ago

Remembering those who have died in the world's deadliest Ebola outbreak, Liberia's president opened one of the country's largest Ebola treatment centers in Monrovia on Friday amid hopes that the disease is ...

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.