Fever during pregnancy associated with birth defects

Fever during pregnancy associated with birth defects
Fever during pregnancy is associated with adverse health outcomes for the offspring, according to research published online Feb. 24 in Pediatrics.

(HealthDay)—Fever during pregnancy is associated with adverse health outcomes for the offspring, according to research published online Feb. 24 in Pediatrics.

Julie Werenberg Dreier, M.S.P.H., of the University of Southern Denmark in Esbjerg, and colleagues conducted a systematic review of the literature to identify cohort and case-control studies addressing of prenatal exposure to fever. The relation between maternal fever during pregnancy and child health outcomes was assessed. Preterm births were excluded.

According to the researchers, the evidence suggests that fever exposure during the first trimester increases, by 1.5 to nearly three times, the risk of , , and oral clefts. There was no strong evidence of a dose-response effect. Antipyretic medications used during febrile episodes in the mother may have a protective effect for the fetus.

"We found substantial evidence to support the contention that maternal fever during pregnancy may negatively affect offspring health," the authors write.

More information: Abstract
Full Text (subscription or payment may be required)

add to favorites email to friend print save as pdf

Related Stories

Sleep-disordered breathing may worsen pregnancy outcomes

Jan 05, 2014

(HealthDay)—Evidence from published observational studies suggests that maternal sleep-disordered breathing is associated with increased risk of gestational hypertension and gestational diabetes, according ...

Recommended for you

With kids in school, parents can work out

10 minutes ago

(HealthDay)—Back-to-school time provides an opportunity for parents to develop an exercise plan that fits into the family schedules, an expert suggests.

Obama offers new accommodations on birth control

4 hours ago

The Obama administration will offer a new accommodation to religious nonprofits that object to covering birth control for their employees. The measure allows those groups to notify the government, rather than their insurance ...

Use a rule of thumb to control how much you drink

4 hours ago

Sticking to a general rule of pouring just a half glass of wine limits the likelihood of overconsumption, even for men with a higher body mass index. That's the finding of a new Iowa State and Cornell University ...

User comments