Coronary artery calcium score could help guide aspirin therapy

Coronary artery calcium score could help guide aspirin therapy

(HealthDay)—For those who have an elevated coronary artery calcium (CAC) score, aspirin therapy may be beneficial for primary prevention of coronary heart disease (CHD), according to research published online May 6 in Circulation: Cardiovascular Quality and Outcomes.

Michael D. Miedema, M.D., M.P.H., of Harvard Medical School in Boston, and colleagues analyzed data for 4,229 participants from the Multi-Ethnic Study of Atherosclerosis to assess the use of CAC scores as a guide to selecting aspirin therapy for of CHD.

The researchers found that individuals with a CAC score of 100 or greater had an estimated net benefit for use of aspirin regardless of 10-year CHD Framingham Risk Score (FRS) (estimated five-year number needed to treat, 173 for <10 percent FRS and 92 for ≥10 percent FRS; estimated five-year number to harm of 442 for a major bleed). In contrast, individuals with a CAC score of zero had unfavorable estimations for use of to prevent CHD (estimated five-year number needed to treat, 2,036 for <10 percent FRS and 808 for ≥10 percent FRS; estimated five-year number to harm of 442 for a major bleed).

"For the primary prevention of , Multi-Ethnic Study of Atherosclerosis participants with CAC ≥100 had favorable risk/benefit estimations for aspirin use while participants with zero CAC were estimated to receive net harm from aspirin," the authors write.

More information: Abstract
Full Text (subscription or payment may be required)

add to favorites email to friend print save as pdf

Related Stories

Coronary artery calcium predicts cardio death in T2DM

Jan 18, 2013

(HealthDay)—In addition to traditional cardiovascular disease risk factors, in patients with type 2 diabetes, coronary artery calcium (CAC) predicts the risk of cardiovascular death, according to a study ...

Recommended for you

Cerebrovascular reserve-based strategy is cost-effective

Jan 29, 2015

(HealthDay)—A decision rule based on assessment of cerebrovascular reserve (CVR) seems to be cost-effective for prevention of stroke in asymptomatic patients with carotid artery stenosis, according to a ...

New hypertension guidelines could save lives and money

Jan 28, 2015

Full implementation of new hypertension guidelines could prevent 56,000 cardiovascular disease events (mostly heart attacks and strokes) and 13,000 deaths each year, without increasing overall health care costs, an analysis ...

Manchester United's rising stars revolutionize heart health

Jan 28, 2015

A unique research project to identify the effects of exercise on young hearts has been announced today [Wednesday 28 January 2015]. Manchester United's Academy players are being put through their paces having their hearts ...

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.