ESPID: Hypovitaminosis D linked to TB infection in children

ESPID: hypovitaminosis D linked to TB infection in children

(HealthDay)—Hypovitaminosis D is associated with tuberculosis infection in children, according to a study presented at the annual meeting of the European Society for Paediatric Infectious Diseases, held from May 6 to 10 in Dublin.

Elisabetta Venturini, M.D., from the University of Florence in Italy, and colleagues examined serum vitamin D levels in children with latent and in a multicenter observational study conducted in three pediatric centers in Italy and the United Kingdom. Participants included 996 children screened for tuberculosis who had undergone vitamin D measurements.

The researchers found that 4.4 percent of the children had active tuberculosis, 13.9 percent had , and 81.7 percent were controls. The prevalence of hypovitaminosis D was 47 percent overall, 58 percent in the latent tuberculosis group, and 75 percent in the active tuberculosis group (P < 0.0001). In multivariate analysis, the risk of hypovitaminosis D was increased for children with latent and active tuberculosis, compared with controls (relative risk, 1.61 and 4.587, respectively).

"[These] data should alert the physicians about the need of vitamin D supplementation in with low vitamin D status, since this is also important to prevent rickets—another disease that has recently reemerged in developed countries," Venturini said in a statement.

More information: More Information

add to favorites email to friend print save as pdf

Related Stories

Potential new drug for tuberculosis

Aug 05, 2013

A new drug capable of inhibiting growth of Mycobacterium tuberculosis is reported this week in Nature Medicine. The findings may improve therapeutic options for the treatment of drug resistant tuberculosis (TB). ...

Faster screening test to identify tuberculosis

Mar 03, 2014

With 9 million new cases and 2 million deaths annually, Tuberculosis is the second most prevalent and deadliest infectious disease worldwide. As an airborne disease, it spreads easily and is very contagious. ...

Recommended for you

Sierra Leone: WHO too slow to help doc with Ebola

3 hours ago

Sierra Leone accused the World Health Organization on Monday of being "sluggish" in facilitating an evacuation of a doctor who died from Ebola before she could be sent out of the country for medical care.

Dutch doctors feared to have Ebola leave hospital

4 hours ago

Two Dutch doctors flown home from west Africa after fears they might have been contaminated with the killer Ebola virus have left hospital "in good health," their employer, the Lion Heart Medical Centre, said Monday.

Strategic self-sabotage? MRSA inhibits its own growth

9 hours ago

Scientists at the University of Western Ontario have uncovered a bacterial mystery. Against all logic, the most predominant strain of methicillin-resistant Staphylococcus aureus (MRSA) in North American produces an enzyme ...

US works to step up Ebola aid, but is it enough?

11 hours ago

The American strategy on Ebola is two-pronged: Step up desperately needed aid to West Africa and, in an unusual step, train U.S. doctors and nurses for volunteer duty in the outbreak zone. At home, the goal ...

User comments