Fitness impacts concentric remodeling, diastolic function

Fitness impacts concentric remodeling, diastolic function

(HealthDay)—Low cardiorespiratory fitness is associated with increased concentricity and diastolic dysfunction, according to a study published in the April issue of the Journal of the American College of Cardiology: Heart Failure.

Stephanie K. Brinker, M.D., from the University of Texas Southwestern Medical Center in Dallas, and colleagues estimated in participants (1,678 men and 1,247 women) of the Cooper Center Longitudinal Study. Participants received an echocardiogram from 1999 to 2011 and were categorized into age-specific quartiles of fitness, with quartile 1 representing low fitness.

The researchers found that higher levels of mid-life fitness (metabolic equivalents) correlated with larger indexed left atrial volume and indexed left ventricular end-diastolic diameter. There was also a correlation for higher level of fitness with a smaller relative wall thickness and E/e' ratio. No significant association was observed for low fitness with left ventricular systolic function.

"Low fitness is associated with a higher prevalence of concentric remodeling and , suggesting that exercise may lower risk through its effect on favorable cardiac remodeling and improved ," the authors write.

Two authors disclosed financial ties to the pharmaceutical and medical device industries.

More information: Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

add to favorites email to friend print save as pdf

Related Stories

Getting fit in middle age can reduce heart failure risk

May 15, 2013

Middle aged and out of shape? It's not too late to get fit—and reduce your risk for heart failure, according to research presented at the American Heart Association's Quality of Care and Outcomes Research Scientific Sessions ...

Recommended for you

Alternate approach to traditional CPR saves lives

43 minutes ago

A new study shows that survival and neurological outcomes for patients in cardiac arrest can be improved by adding extracorporeal membrane oxygenation (ECMO) when performing cardiopulmonary resuscitation (CPR). The study ...

Viagra protects the heart beyond the bedroom

Oct 20, 2014

Viagra could be used as a safe treatment for heart disease, finds new research published today in the open access journal BMC Medicine. The study reveals that long-term daily treatment of Viagra can provide protection for th ...

User comments