Study finds rising incidence of acute pancreatitis in hospitalized children

May 7, 2014

The largest investigation to date has found a significant increase in the number of acute pancreatitis (AP) cases in hospitalized children in the United States.

The new study, in the PLOS ONE journal found a 51 percent increase in the primary diagnosis of AP from 2000 to 2009. The number increased from 6,350 in 2000 to 9,561 in 2009.

The study looked at of patients 20 years old and younger using a federal 's inpatient database. From 2000 to 2009, they identified 55,012 cases of AP in hospitalized children ages 1 – 20.

According to the study's principal investigator, Thomas J. Sferra, MD, Division Chief of Pediatric Gastroenterology, Hepatology and Nutrition at UH Rainbow Babies & Children's Hospital and Associate Professor of Pediatrics at Case Western Reserve University School of Medicine, hospitalized children with AP had longer hospital stays and higher charges. And AP was more likely to occur in children older than 5 years of age.

AP is the reversible inflammation of the pancreatic parenchyma. In children the most frequently identified causes of AP are biliary tract disease, medication adverse effect, systemic disease and trauma.

"The reason for this large increase in cases in is not clear," said Dr. Sferra. "Though the incidence of AP is increasing, there has been an improvement in the mortality and length of stay of these patients. These data provide a good foundation for future studies to increase our understanding of the disease."

Explore further: Study finds dramatic increase in hospitalization of US children with inflammatory bowel disease

Related Stories

Chronic illness puts pediatric trauma patients at higher risk

August 6, 2013

In a recent study published in the Journal of Trauma and Acute Care Surgery, researchers from the Center for Injury Research and Policy in The Research Institute at Nationwide Children's Hospital found that pediatric trauma ...

Study finds ADHD and trauma often go hand in hand

May 6, 2014

When children struggle with focusing on tasks, staying organized, controlling their behavior and sitting still, they may be evaluated for attention-deficit/hyperactivity disorder (ADHD). Clinicians, however, shouldn't stop ...

Recommended for you

Monkeys in Asia harbor virus from humans, other species

November 19, 2015

When it comes to spreading viruses, bats are thought to be among the worst. Now a new study of nearly 900 nonhuman primates in Bangladesh and Cambodia shows that macaques harbor more diverse astroviruses, which can cause ...

One-step test for hepatitis C virus infection developed

November 14, 2015

UC Irvine Health researchers have developed a cost-effective one-step test that screens, detects and confirms hepatitis C virus (HCV) infections. Dr. Ke-Qin Hu, director of hepatology services, will present findings at the ...

Computer model reveals deadly route of Ebola outbreak

November 10, 2015

Using a novel statistical model, a research team led by Columbia University's Mailman School of Public Health mapped the spread of the 2014-2015 Ebola outbreak in Sierra Leone, providing the most detailed picture to date ...


Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.