Migraine attacks increase following stress

May 5, 2014 by Deirdre Branley
Credit: Sasha Wolff/Wikipedia

(Medical Xpress)—Migraine sufferers who experienced reduced stress from one day to the next are at significantly increased risk of migraine onset on the subsequent day, according to a new study conducted by researchers at the Montefiore Headache Center and Albert Einstein College of Medicine at Yeshiva University. Stress has long been believed to be a common headache trigger. In this study, researchers found that relaxation following heightened stress was an even more significant trigger for migraine attacks. Findings may aid in recommending preventive treatments and behavioral interventions. The study was published online today in Neurology, the medical journal of the American Academy of Neurology.

Migraine is a chronic condition that affects approximately 38 million Americans. To examine headache triggers, investigators at the Montefiore Headache Center and Einstein conducted a three month electronic daily diary study which captured 2,011 diary records and 110 eligible attacks in 17 participants. The study compared levels of stress and reduction in stress as predictors of headache.

"This study demonstrates a striking association between reduction in perceived stress and the occurrence of ," said study lead author Richard Lipton, M.D., director, Montefiore Headache Center, professor and vice chair of and the Edwin S. Lowe Chair in Neurology, Einstein. "Results were strongest during the first six hours where decline in stress was associated with a nearly five-fold increased risk of migraine onset. The hormone cortisol, which rises during times of stress and reduces pain, may contribute to the triggering of headache during periods of relaxation."

Data were collected using a custom-programmed electronic diary. Each day participants recorded information about , two types of stress ratings and common migraine triggers, such as hours of sleep, certain foods, drinks and alcohol consumed, and menstrual cycle. They also recorded their mood each day, including feeling happy, sad, relaxed, nervous, lively and bored.

"This study highlights the importance of stress management and healthy lifestyle habits for people who live with migraine," said Dawn Buse, Ph.D., director, Behavioral Medicine, Montefiore Headache Center, associate professor, Clinical Neurology, Einstein, and study co-author. "It is important for people to be aware of rising and attempt to relax during periods of rather than allowing a major build up to occur. This could include exercising or attending a yoga class or may be as simple as taking a walk or focusing on one's breath for a few minutes."

Explore further: Few migraine sufferers referred for behavioral treatments

Related Stories

Got the sniffles? Migraines spike with allergies and hay fever

November 25, 2013

People with migraine who also battle allergies and hay fever (rhinitis) endure a more severe form of headaches than their peers who struggle with migraine, but aren't affected by the seasonal or year-round sniffles, according ...

Don't let migraines ruin your holidays

December 26, 2013

(HealthDay)—The holidays can challenge the estimated 30 million migraine sufferers in the United States as they try to deal with crowds, travel delays, stress and other potential headache triggers.

Does more stress equal more headaches?

February 19, 2014

A new study provides evidence for what many people who experience headache have long suspected—having more stress in your life leads to more headaches. The study released today will be presented at the American Academy ...

Migraine attacks increase following stress 'let-down'

March 26, 2014

Migraine sufferers who experienced reduced stress from one day to the next are at significantly increased risk of migraine onset on the subsequent day, according to a new study conducted by researchers at the Montefiore Headache ...

Recommended for you

Brain structure generates pockets of sleep within the brain

October 13, 2015

Sleep is usually considered an all-or-nothing state: The brain is either entirely awake or entirely asleep. However, MIT neuroscientists have discovered a brain circuit that can trigger small regions of the brain to fall ...

Closer view of the brain

October 13, 2015

For Harvard neurobiologist Jeff Lichtman, the question hasn't been whether scientists will ever understand the brain, but how closely they'll have to look before they do.


Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.