No correlation between baby formulas and development of diabetes-associated autoantibodies

June 16, 2014

There is no correlation between the consumption of a cow's milk-based formula or hydrolyzed protein formula and the development of diabetes-associated autoantibodies in children younger than seven, according to a worldwide research study published in the Journal of the American Medical Association (JAMA).

The Trial to Reduce Insulin Dependent Diabetes Mellitus in the Genetically at Risk (TRIGR) study, which examines possible reduction in autoantibodies associated with type 1 diabetes, tracked children genetically predisposed to type 1 diabetes for seven years.

It was conducted in 78 centers in 15 countries, including the U.S and Canada, and will continue to receive funding from the National Institutes of Health to collect data up to the children's 10th birthday. A pilot study in Finland with a smaller, homogeneous population showed that weaning infants to an extensively hydrolyzed casein formula decreased the cumulative occurrence of diabetes-associated autoantibodies in children who have a first-degree relative with type 1 diabetes and an increased genetic risk.

Anita Nucci, assistant professor of nutrition at Georgia State University, is the U.S. coordinator and the North America nutrition coordinator for TRIGR. She notes that while there is no correlation between cow's milk protein and the that result in type 1 diabetes, the second end-point of the TRIGR study is the development of type 1 diabetes by 10 years of age.

"The NIH's continued support validates the possibility the connection with cow's and type 1 diabetes may appear a little later in the lives of children who live outside Finland or that hydrolyzed formula affects the rate of progression of autoimmunity to in high-risk children," says Nucci.

Some genetic subgroups may carry a higher risk for diabetes and cow's milk proteins. Scandinavia is the region with the highest incidence of in the world.

Explore further: Hydrolyzed formula does not reduce diabetes-associated autoantibodies in at-risk infants

Related Stories

Type 1 diabetes: Vitamin D deficiency occurs in an early stage

February 27, 2014

Vitamin D is known as a major regulator of calcium levels and bone metabolism. Furthermore, it also influences the immune system. Previous studies have shown that patients with recently diagnosed type 1 diabetes have significantly ...

Recommended for you

Low-carb diet may aid your metabolism

December 2, 2016

(HealthDay)—Eating low-carbohydrate meals may lead to healthy changes in a woman's metabolism that don't occur when consuming higher-carbohydrate meals, a small study suggests.

Research shows nerve growth protein controls blood sugar

November 14, 2016

Research led by a Johns Hopkins University biologist demonstrates the workings of a biochemical pathway that helps control glucose in the bloodstream, a development that could potentially lead to treatments for diabetes.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.