For gastric bypass patients, percent of weight loss differs by race/ethnicity, study finds

Non-Hispanic white patients who underwent a gastric bypass procedure lost slightly more weight over a three-year period than Hispanic or black patients, according to a Kaiser Permanente study published in the journal Surgery for Obesity and Related Diseases. The study also examined two types of bariatric surgery and found that patients who underwent the now common gastric bypass procedure lost more weight over the same period than patients who underwent the more recently developed vertical sleeve gastrectomy procedure.

Researchers examined the Kaiser Permanente electronic health records of more than 20,000 racially and ethnically diverse patients in Southern California who underwent from 2004 through May 2013. They found that, on average, at three years following surgery, non-Hispanic white patients lost 63 percent of their ; Hispanic patients lost 59 percent; and black patients lost 56 percent. With vertical sleeve gastrectomy patients, the researchers found no significant differences between racial or ethnic groups in the percentage of excess weight lost.

The study also found that overall, gastric bypass patients lost an average of 59 percent of excess weight (an average 81.5 pounds) and vertical sleeve gastrectomy patients lost an average of 46 percent (57.6 pounds) after three years of follow-up.

"Studies have shown that bariatric surgery is associated with sustainable weight loss for patients with extreme obesity, but there is very little research to show how these procedures affect persons of different races and ethnicities, especially in the long term," said study lead author Karen J. Coleman, PhD, of the Kaiser Permanente Southern California Department of Research & Evaluation. "To address the current gaps in the knowledge about bariatric surgery, we created a registry of patients who underwent surgery to monitor quality and safety outcomes and assist clinicians who are caring for these patients after their surgery."

Bariatric surgery is an option for people who cannot lose weight by other means or who suffer from serious health problems related to extreme obesity. Gastric bypass is the most commonly performed bariatric surgical procedure and involves the creation of a small pouch at the top of the stomach for food intake, limiting the amount of food that can be consumed, in addition to a bypass of the upper small intestine to limit food absorption. Vertical sleeve gastrectomy is a procedure involving the removal of part of the stomach with the remaining portion formed into a tube, limiting food intake. This surgery has most often been conducted on patients who are too heavy to safely have other types of weight-loss surgery because the procedure can be completed more quickly and has less risk of long-term complications.

According to the Centers for Disease Control and Prevention, nearly 34 percent of U.S. adults are considered to be obese, with a body mass index of 30 or greater, and nearly 6 percent of Americans are considered to have extreme obesity, with a BMI of 40 or greater. Obesity has been found to be more common among black and Hispanic populations, with nearly 50 percent of blacks, 39 percent of Hispanics and 34 percent of non-Hispanic whites considered to be obese, according to the National Institutes of Health. Obese individuals are often at a greater risk of health problems, including coronary heart disease, high blood pressure, stroke and type 2 diabetes. The NIH considers extreme obesity a chronic condition that is hard to treat with diet and exercise alone.

"Even though some patients may not lose as much weight as others, the weight regain rate at three years is still very low for all patients, regardless of their racial or ethnic background. This supports the success of bariatric surgery for weight control in persons who have extreme obesity," said Coleman. "We believe our study provides an opportunity for health care providers to potentially develop more culturally sensitive post-surgical programs to improve success rates for populations struggling with loss."

This study is part of Kaiser Permanente's broader efforts to deliver transformational health research focusing on bariatric surgery and its impact on patients with . Last October, a Kaiser Permanente study found that the impact of bariatric surgery on risk factors for cardiovascular disease depends upon a variety of factors, including the type of surgery, sex of the patient, race and ethnic background and pre-surgery body mass index. A separate Kaiser Permanente study also found that the chronic use of prescription painkillers, also known as opioids, among obese prior to bariatric surgery continues after .

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