Proteins in urine could play important role in stress incontinence

Proteins in urine could play important role in stress incontinence
Proteins in urine could play important role in stress incontinence

Incontinence is the world's most common chronic condition. Around ten per cent of Austrians are affected by it. However the problem continues to be a taboo subject: two out of three sufferers do not talk about it, preventing access to successful treatment. Stress incontinence, in which urine is lost involuntarily when coughing, laughing or sneezing, is the most common form of incontinence, affecting 60 per cent of all cases. How it develops is largely unresearched. Scientists at the MedUni Vienna have now been able to demonstrate that proteins in the urine could play an important role.

Researchers at the University Department of Gynaecology, Core Facilities Proteomics and the Institute of Laboratory Medicine (KILM) at the MedUni Vienna are currently investigating the urine proteome, i.e. all of the proteins it contains, in people with and without . The first result: "People with urinary incontinence have more and different proteins. It is also apparent that certain inflammatory mechanisms have a role to play and that proteins are involved that indicate prior cell conversion," says Heinz Kölbl, Head of the Clinical Department of General Gynaecology and Gynaecological Oncology at the MedUni Vienna's University Department of Gynaecology.

From a diagnostic perspective, these findings could lead to the proteome being the clue to who is at risk of developing and who isn't. "But the main thing we are expecting is information on how this condition actually develops," says Kölbl.

add to favorites email to friend print save as pdf

Related Stories

Clinical review published in JAMA

Jun 06, 2014

Many women experience bothersome urine loss with laughing, coughing and sneezing (stress urinary incontinence) AND on their way to the bathroom (urge urinary incontinence). When women experience both types of urine leakage, ...

Incontinence takes mental toll on younger women

Jun 14, 2013

New research from the University of Adelaide shows middle-aged women are more likely to suffer depression from a common medical problem that they find too embarrassing to talk about: urinary incontinence.

Recommended for you

Nigeria death shows Ebola can spread by air travel

10 hours ago

(AP)—Nigerian health authorities raced to stop the spread of Ebola on Saturday after a man sick with one of the world's deadliest diseases brought it by plane to Lagos, Africa's largest city with 21 million ...

Trial in salmonella outbreak to start in Georgia

10 hours ago

(AP)—Three people accused of scheming to manufacture and ship salmonella-tainted peanuts that killed nine people and sickened more than 700 are set to go to trial this week in Georgia.

Remote tribe members enter another village, catch flu

18 hours ago

Advocates for indigenous tribes are worried over incidents last month when some members of one of the last uncontacted tribes in the Peru/Brazil region, across borders, left their home in Peru and entered ...

Nigeria on red alert after first Ebola death

Jul 26, 2014

Nigeria was on alert against the possible spread of Ebola on Saturday, a day after the first confirmed death from the virus in Lagos, Africa's biggest city and the country's financial capital.

User comments