Higher risk of vascular events with polymyalgia rheumatica

Higher risk of vascular events with polymyalgia rheumatica
Polymyalgia rheumatica is associated with an increased risk of vascular events, according to research published online July 28 in CMAJ, the journal of the Canadian Medical Association.

(HealthDay)—Polymyalgia rheumatica is associated with an increased risk of vascular events, according to research published online July 28 in CMAJ, the journal of the Canadian Medical Association.

Adam T. Hancock, M.B.Ch.B., M.Phil., of Keele University in the United Kingdom, and colleagues conducted a prospective study of 3,249 patients with polymyalgia rheumatica matched with 12,735 patients without the condition. The authors sought to assess the association between polymyalgia rheumatica and risk of vascular events, including cardiovascular, cerebrovascular, and peripheral vascular events.

The researchers found that, over a median follow-up period of 7.8 years (interquartile range, 3.3 to 12.4 years), patients with polymyalgia rheumatica had a higher rate of vascular events than patients without the condition (36.1 versus 12.2 per 1,000 person-years; adjusted hazard ratio, 2.6; 95 percent confidence interval, 2.4 to 2.9). Patients with polymyalgia rheumatica had higher risk of all types of vascular events. The increase in risk of vascular events associated with polymyalgia rheumatica was higher in those with early disease and in those younger than 60 years at the time of diagnosis.

"As with other forms of , patients with polymyalgia rheumatica should have their identified and actively managed to reduce this excess risk," the authors write.

More information: Abstract
Full Text

add to favorites email to friend print save as pdf

Related Stories

Recommended for you

Adrenal sex hormone level may predict heart disease risk

16 hours ago

(HealthDay)—Blood levels of the adrenal sex hormone dehydroepiandrosterone (DHEA) and its sulfate (DHEA-S) may predict an increased risk of coronary heart disease (CHD) in elderly men, according to a study ...

Researchers aim to simplify life saving drug

Oct 29, 2014

Heparin, the life saving blood thinner used in major surgeries and treatment of heart diseases, is a complicated drug but a research team from the University of British Columbia has set out to make its use a lot safer by ...

Frequent readmissions, high costs after cardiac arrest

Oct 29, 2014

(HealthDay)—Frequent readmissions and high inpatient costs are seen among older survivors of in-hospital cardiac arrest, according to a study published online Oct. 28 in Circulation: Cardiovascular Quality an ...

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.