Higher risk of vascular events with polymyalgia rheumatica

July 31, 2014
Higher risk of vascular events with polymyalgia rheumatica
Polymyalgia rheumatica is associated with an increased risk of vascular events, according to research published online July 28 in CMAJ, the journal of the Canadian Medical Association.

(HealthDay)—Polymyalgia rheumatica is associated with an increased risk of vascular events, according to research published online July 28 in CMAJ, the journal of the Canadian Medical Association.

Adam T. Hancock, M.B.Ch.B., M.Phil., of Keele University in the United Kingdom, and colleagues conducted a prospective study of 3,249 patients with polymyalgia rheumatica matched with 12,735 patients without the condition. The authors sought to assess the association between polymyalgia rheumatica and risk of vascular events, including cardiovascular, cerebrovascular, and peripheral vascular events.

The researchers found that, over a median follow-up period of 7.8 years (interquartile range, 3.3 to 12.4 years), patients with polymyalgia rheumatica had a higher rate of vascular events than patients without the condition (36.1 versus 12.2 per 1,000 person-years; adjusted hazard ratio, 2.6; 95 percent confidence interval, 2.4 to 2.9). Patients with polymyalgia rheumatica had higher risk of all types of vascular events. The increase in risk of vascular events associated with polymyalgia rheumatica was higher in those with early disease and in those younger than 60 years at the time of diagnosis.

"As with other forms of , patients with polymyalgia rheumatica should have their identified and actively managed to reduce this excess risk," the authors write.

Explore further: American College of Rheumatology releases first classification criteria for polymyalagia rheumatica

More information: Abstract
Full Text

Related Stories

Glycemic variability elevates risk of vascular events, death

May 16, 2014

(HealthDay)—Visit-to-visit variability (VVV) in glycated hemoglobin (HbA1c) and fasting glucose correlate with major adverse outcomes for patients with type 2 diabetes, according to a study published online May 8 in Diabetes ...

Recommended for you

Painkillers linked to heart failure: study

September 29, 2016

Widely used prescription and non-prescription painkillers are associated with an increased risk of hospital admission for heart failure, according to a study released Thursday.

Researchers mine Twitter for cardiovascular disease research

September 28, 2016

For years, marketers and other commercial data-miners have been using Twitter's vast database of "tweets" to gauge consumer attitudes and track events. Now medical researchers are getting in on the trend. Researchers from ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.